Voltammetric sensing system for the detection of cholesterol based on the Ni-bisurea-pyrographite composite

Anastasia A. Lukina, Daniar V. Ismailov, Alexander P. Ilyin, Ksenia V. Derina, Elena I. Korotkova

Результат исследований: Материалы для книги/типы отчетовМатериалы для конференции

Аннотация

Cholesterol plays a crucial role in the human body. High cholesterol level in blood is a marker of CVDs. Therefore, cholesterol determination techniques are necessary for clinical practice. Currently used cholesterol determination techniques involve enzymes or expensive and complicated equipment. Electrochemical techniques are widely spread in test-systems and sensors construction. Novel modification procedure for enzymeless cholesterol determination is suggested in this study. The electrochemical behavior of cholesterol on modified electrode was studied with the usage of cyclic and differential pulse voltammetry. Obtained concentration range is linear from 0.1 up to 100 mM a conditions close to physiological (pH=6.86) with a quantification limit of 0.01 mM. Besides, the electrode surface morphology and pH-effect were studied. The developed technique is promising for the rapid determination of total cholesterol in blood.

Язык оригиналаАнглийский
Название основной публикацииHigh Technology
Подзаголовок основной публикацииResearch and Applications 2017
РедакторыGeorgii E. Osokin, Ekaterina A. Kulinich
ИздательTrans Tech Publications Ltd
Страницы250-255
Число страниц6
ISBN (печатное издание)9783035712810
DOI
СостояниеОпубликовано - 1 янв 2018
Событие6th International Conference for Young Scientists High Technology: Research and Applications, HTRA 2017 - Tomsk, Российская Федерация
Продолжительность: 27 ноя 201729 ноя 2017

Серия публикаций

НазваниеKey Engineering Materials
Том769 KEM
ISSN (печатное издание)1013-9826

Конференция

Конференция6th International Conference for Young Scientists High Technology: Research and Applications, HTRA 2017
СтранаРоссийская Федерация
ГородTomsk
Период27.11.1729.11.17

ASJC Scopus subject areas

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering

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  • Цитировать

    Lukina, A. A., Ismailov, D. V., Ilyin, A. P., Derina, K. V., & Korotkova, E. I. (2018). Voltammetric sensing system for the detection of cholesterol based on the Ni-bisurea-pyrographite composite. В G. E. Osokin, & E. A. Kulinich (Ред.), High Technology: Research and Applications 2017 (стр. 250-255). (Key Engineering Materials; Том 769 KEM). Trans Tech Publications Ltd. https://doi.org/10.4028/www.scientific.net/KEM.769.250