Voltammetric and amperometric determination of 2,4-dinitrophenol metabolites

Hana Dejmkova, Anca Iulia Stoica, Jiri Barek, Jiri Zima

Результат исследований: Материалы для журналаСтатья

5 Цитирования (Scopus)

Выдержка

Methods for determination of 2-amino-4-nitrophenol and 4-amino-2- nitrophenol, metabolites of 2,4-dinitrophenol, were developed using differential pulse (DP) voltammetry and HPLC with amperometric and spectrophotometric detection. The applicability of these methods was tested by the determination of the analytes in model samples of urine after preliminary separation by solid-phase extraction. Voltammetry enabled parallel determination of both analytes, but its application in real matrix was severely limited due to the interference of other compounds present in urine. HPLC allowed the determination in real urine matrix down to micromolar concentrations; amperometric detection proved to be more sensitive and selective than the spectrophotometric one.

Язык оригиналаАнглийский
Страницы (с-по)2594-2598
Число страниц5
ЖурналTalanta
Том85
Номер выпуска5
DOI
СостояниеОпубликовано - 15 окт 2011
Опубликовано для внешнего пользованияДа

Отпечаток

2,4-Dinitrophenol
Voltammetry
Metabolites
4-amino-2-nitrophenol
2-amino-4-nitrophenol

ASJC Scopus subject areas

  • Analytical Chemistry

Цитировать

Voltammetric and amperometric determination of 2,4-dinitrophenol metabolites. / Dejmkova, Hana; Stoica, Anca Iulia; Barek, Jiri; Zima, Jiri.

В: Talanta, Том 85, № 5, 15.10.2011, стр. 2594-2598.

Результат исследований: Материалы для журналаСтатья

Dejmkova, Hana ; Stoica, Anca Iulia ; Barek, Jiri ; Zima, Jiri. / Voltammetric and amperometric determination of 2,4-dinitrophenol metabolites. В: Talanta. 2011 ; Том 85, № 5. стр. 2594-2598.
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AU - Stoica, Anca Iulia

AU - Barek, Jiri

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N2 - Methods for determination of 2-amino-4-nitrophenol and 4-amino-2- nitrophenol, metabolites of 2,4-dinitrophenol, were developed using differential pulse (DP) voltammetry and HPLC with amperometric and spectrophotometric detection. The applicability of these methods was tested by the determination of the analytes in model samples of urine after preliminary separation by solid-phase extraction. Voltammetry enabled parallel determination of both analytes, but its application in real matrix was severely limited due to the interference of other compounds present in urine. HPLC allowed the determination in real urine matrix down to micromolar concentrations; amperometric detection proved to be more sensitive and selective than the spectrophotometric one.

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