Optical coherence tomography (OCT) is a new, noninvasive, noncontact in vivo imaging technology. We demonstrated that the OCT can be used as a sufficient technique for nanocomposite microcapsule visualization in a liquid medium. As a model system we choose a water/glycerol mixture with viscosity in a variable range from 1.01 to 1.41×10 3 mPa s, including viscosity of a blood plasma. We have found that tomography spatial resolution is enough to visualize capsules and their aggregates in liquids and to estimate their concentration via two-dimensional (2D) tomography scan analysis. In our experimental conditions microcapsule concentration measured by OCT was 3.9×10 7 cm -3 and this value correlated well with the concentration measured in a counting chamber (1.9×10 7 cm -3). We also demonstrated the possibility to control capsule spatial distribution in glycerol solutions by external magnetic field and determined the dependence of capsule sedimentation time on the liquid medium viscosity.
ASJC Scopus subject areas
- Physics and Astronomy (miscellaneous)