Validation of a GC-MS Method for Quantitative Determination of Cyclohexanone by Oxidative Cleavage

E. V. Podrezova, M. S. Lar’kina, M. S. Yusubov, M. V. Belousov, M. K. Zamanova, S. V. Krivoshchekov

Результат исследований: Материалы для журналаСтатья

Аннотация

A GC method for quantitative determination of cyclohexanone by oxidative cleavage was proposed. The research was aimed at the development of a simple, rapid, and effective GC method for quantitative analysis of cyclohexanone in a reaction mixture. Chlorobenzene was used as an internal standard. Qualitative analysis compared mass spectra obtained for each component with mass spectra from the National Institute of Standards and Technology (NIST) database. The method was validated for specificity, linearity, accuracy, robustness, repeatability, and intralaboratory precision.

Язык оригиналаАнглийский
Страницы (с-по)1021-1025
Число страниц5
ЖурналPharmaceutical Chemistry Journal
Том52
Номер выпуска12
DOI
СостояниеОпубликовано - 15 мар 2019

ASJC Scopus subject areas

  • Pharmacology
  • Drug Discovery

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