TY - JOUR
T1 - Ultrastructure of Rat Kidneys after Intravenous Administration of Modified Magnetite Nanoparticles
AU - Mil’to, I. V.
AU - Sukhodolo, I. V.
AU - Ivanova, V. V.
AU - Yusubov, M. S.
PY - 2017/12/1
Y1 - 2017/12/1
N2 - The ultrastructure of nephrocytes of the proximal and distal convoluted tubules, podocytes, mesangial cells, and macrophages of the interstitial connective tissue was studied after single intravenous administration of magnetite nanoparticles modified with chitosan (magnetic nanospheres) or lipids (magnetic liposomes). Transmission electron microscopy showed ultrastructural features of absorption of magnetite nanoparticles. The shape, size, and number of vesicles containing nanoparticles in nephrocytes of convoluted tubules and macrophages after administration of the suspensions of magnetic nanospheres and magnetic liposomes were described.
AB - The ultrastructure of nephrocytes of the proximal and distal convoluted tubules, podocytes, mesangial cells, and macrophages of the interstitial connective tissue was studied after single intravenous administration of magnetite nanoparticles modified with chitosan (magnetic nanospheres) or lipids (magnetic liposomes). Transmission electron microscopy showed ultrastructural features of absorption of magnetite nanoparticles. The shape, size, and number of vesicles containing nanoparticles in nephrocytes of convoluted tubules and macrophages after administration of the suspensions of magnetic nanospheres and magnetic liposomes were described.
KW - magnetic liposomes
KW - magnetic nanospheres
KW - magnetite nanoparticles
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U2 - 10.1007/s10517-017-3962-0
DO - 10.1007/s10517-017-3962-0
M3 - Article
AN - SCOPUS:85034965316
VL - 164
SP - 218
EP - 222
JO - Bulletin of Experimental Biology and Medicine
JF - Bulletin of Experimental Biology and Medicine
SN - 0007-4888
IS - 2
ER -