Ultrasonically assisted fabrication of vaterite submicron-sized carriers

Аннотация

Ultrasonically accomplished precipitation of calcium carbonate was demonstrated as a novel beneficial method for the formation of porous submicron vaterite particles with low dispersity, high mass yield, and the "scaling up" possibility. The effect of sonication on the size and crystallographic phase of formed particles was investigated by comparing this method with a magnetic stirring and non-stirring interfusion. By virtue of their porosity, vaterite particles allow the different substance incorporation. The loading properties of synthesized particles were demonstrated for high molecular weight substance (labeled protein), as well as for low molecular one (fluorescent dye). Such features open up perspectives of drug encapsulation and delivery for the vaterite submicron carriers.

Язык оригинала	Английский
Страницы (с-по)	618-624
Число страниц	7
Журнал	Advanced Powder Technology
Том	27
Номер выпуска	2
DOI	https://doi.org/10.1016/j.apt.2016.02.014
Состояние	Опубликовано - 1 мар 2016
Опубликовано для внешнего пользования	Да

ASJC Scopus subject areas

Chemical Engineering(all)
Mechanics of Materials

Доступ к документу

10.1016/j.apt.2016.02.014

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Цитировать

Svenskaya, Y. I., Fattah, H., Zakharevich, A. M., Gorin, D. A., Sukhorukov, G. B., & Parakhonskiy, B. V. (2016). Ultrasonically assisted fabrication of vaterite submicron-sized carriers. Advanced Powder Technology, 27(2), 618-624. https://doi.org/10.1016/j.apt.2016.02.014

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title = "Ultrasonically assisted fabrication of vaterite submicron-sized carriers",

abstract = "Ultrasonically accomplished precipitation of calcium carbonate was demonstrated as a novel beneficial method for the formation of porous submicron vaterite particles with low dispersity, high mass yield, and the {"}scaling up{"} possibility. The effect of sonication on the size and crystallographic phase of formed particles was investigated by comparing this method with a magnetic stirring and non-stirring interfusion. By virtue of their porosity, vaterite particles allow the different substance incorporation. The loading properties of synthesized particles were demonstrated for high molecular weight substance (labeled protein), as well as for low molecular one (fluorescent dye). Such features open up perspectives of drug encapsulation and delivery for the vaterite submicron carriers.",

keywords = "Calcium carbonate, Microparticles, Porous particles, Submicron particles, Ultrasound, Vaterite",

author = "Svenskaya, {Yu I.} and H. Fattah and Zakharevich, {A. M.} and Gorin, {D. A.} and Sukhorukov, {G. B.} and Parakhonskiy, {B. V.}",

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T1 - Ultrasonically assisted fabrication of vaterite submicron-sized carriers

AU - Svenskaya, Yu I.

AU - Fattah, H.

AU - Zakharevich, A. M.

AU - Gorin, D. A.

AU - Sukhorukov, G. B.

AU - Parakhonskiy, B. V.

PY - 2016/3/1

Y1 - 2016/3/1

N2 - Ultrasonically accomplished precipitation of calcium carbonate was demonstrated as a novel beneficial method for the formation of porous submicron vaterite particles with low dispersity, high mass yield, and the "scaling up" possibility. The effect of sonication on the size and crystallographic phase of formed particles was investigated by comparing this method with a magnetic stirring and non-stirring interfusion. By virtue of their porosity, vaterite particles allow the different substance incorporation. The loading properties of synthesized particles were demonstrated for high molecular weight substance (labeled protein), as well as for low molecular one (fluorescent dye). Such features open up perspectives of drug encapsulation and delivery for the vaterite submicron carriers.

AB - Ultrasonically accomplished precipitation of calcium carbonate was demonstrated as a novel beneficial method for the formation of porous submicron vaterite particles with low dispersity, high mass yield, and the "scaling up" possibility. The effect of sonication on the size and crystallographic phase of formed particles was investigated by comparing this method with a magnetic stirring and non-stirring interfusion. By virtue of their porosity, vaterite particles allow the different substance incorporation. The loading properties of synthesized particles were demonstrated for high molecular weight substance (labeled protein), as well as for low molecular one (fluorescent dye). Such features open up perspectives of drug encapsulation and delivery for the vaterite submicron carriers.

KW - Calcium carbonate

KW - Microparticles

KW - Porous particles

KW - Submicron particles

KW - Ultrasound

KW - Vaterite

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