The fabrication of bioresorbable implants for bone defects replacement using computer tomogram and 3D printing

P. G. Kuznetsov, S. I. Tverdokhlebov, S. I. Goreninskii, E. N. Bolbasov, A. V. Popkov, D. E. Kulbakin, E. G. Grigoryev, N. V. Cherdyntseva, E. L. Choinzonov

Результат исследования: Материалы для книги/типы отчетовМатериалы для конференции

Аннотация

The present work demonstrates the possibility of production of personalized implants from bioresorbable polymers designed for replacement of bone defects. The stages of creating a personalized implant are described, which include the obtaining of 3D model from a computer tomogram, development of the model with respect to shape of bone fitment bore using Autodesk Meshmixer software, and 3D printing process from bioresorbable polymers. The results of bioresorbable polymer scaffolds implantation in pre-clinical tests on laboratory animals are shown. The biological properties of new bioresorbable polymers based on poly(lactic acid) were studied during their subcutaneous, intramuscular, bone and intraosseous implantation in laboratory animals. In all cases, there was a lack of a fibrous capsule formation around the bioresorbable polymer over time. Also, during the performed study, conclusions were made on osteogenesis intensity depending on the initial state of bone tissue.

Язык оригиналаАнглийский
Заголовок главной публикацииPhysics of Cancer
Подзаголовок главной публикацииInterdisciplinary Problems and Clinical Applications - Proceedings of the International Conference on Physics of Cancer: Interdisciplinary Problems and Clinical Applications, PC IPCA 2017
РедакторыElazar Y. Gutmanas, Oleg B. Naimark, Yurii P. Sharkeev
ИздательAmerican Institute of Physics Inc.
Том1882
ISBN (электронная версия)9780735415621
DOI
Статус публикацииОпубликовано - 28 сен 2017
СобытиеInternational Conference on Physics of Cancer: Interdisciplinary Problems and Clinical Applications, PC IPCA 2017 - Tomsk, Российская Федерация
Длительность: 23 мая 201726 мая 2017

Конференция

КонференцияInternational Conference on Physics of Cancer: Interdisciplinary Problems and Clinical Applications, PC IPCA 2017
СтранаРоссийская Федерация
ГородTomsk
Период23.5.1726.5.17

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ASJC Scopus subject areas

  • Physics and Astronomy(all)

Цитировать

Kuznetsov, P. G., Tverdokhlebov, S. I., Goreninskii, S. I., Bolbasov, E. N., Popkov, A. V., Kulbakin, D. E., ... Choinzonov, E. L. (2017). The fabrication of bioresorbable implants for bone defects replacement using computer tomogram and 3D printing. В E. Y. Gutmanas, O. B. Naimark, & Y. P. Sharkeev (Ред.), Physics of Cancer: Interdisciplinary Problems and Clinical Applications - Proceedings of the International Conference on Physics of Cancer: Interdisciplinary Problems and Clinical Applications, PC IPCA 2017 (Том 1882). [020040] American Institute of Physics Inc.. https://doi.org/10.1063/1.5001619