The influence of the electron beam irradiation on the parameters of aluminum nanopowder oxidation by heating in air was studied. It was found that the oxidation starts at the temperature in the range from 410° C to 460° C and independent on the radiation dose. The degree of oxidation varied from 44.4 % to 58.3 % and its dependence on the radiation dose was not established. The heat energy release occurred in two stages: at the first stage (up to ∼ 660° C) in general the increase of the thermal effect was observed. At the second oxidation stage of irradiated aluminum nanopowder the growth of the thermal effect also observed. The peak of heat effect achieved by irradiation (45.0 kGy absorbed dose) was 2576 J/g higher than the thermal effect for non-irradiated aluminum nanopowder. The energy stored is an additional motivating factor in the synthesis of composite materials, intermetallic compounds, hydrogen producing reactions and synthesis of various kinds.