The antiviral activity of RNAse Bacillus intermedius in experiments with mice preinfected with street rabies virus

S. V. Gribencha, L. A. Potselueva, I. F. Barinsky, T. G. Balandin, S. M. Deev, I. B. Leshchinskaya

Результат исследований: Материалы для журналаСтатьярецензирование

6 Цитирования (Scopus)

Аннотация

RNAse Bacillus intermedius, when administered once and according to 11 repeated experiments, protected the preliminarily infected CBA mice with street rabies virus (protection of 40-67%; p < 0.01-0.001). A reliable protection of Animals was registered only when RNAse was administered intramuscularly at the virus introduction spot; it was not effective, when the bacterial RNAse was injected in the brain, vein, under the skin or in muscles of a non-infected extremity. Neither did it produce any suppressive effect on the vaccinal antirabic immunity.

Язык оригиналаАнглийский
Страницы (с-по)38-41
Число страниц4
ЖурналVoprosy Virusologii
Том49
Номер выпуска6
СостояниеОпубликовано - 2004

ASJC Scopus subject areas

  • Virology
  • Infectious Diseases

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