Synthesis of 7-aza-5-deazapurine analogues via copper(I)-catalyzed hydroamination of alkynes and 1-iodoalkynes

Larissa B. Krasnova, Jason E. Hein, Valery V. Fokin

Результат исследований: Материалы для журнала › Статья

Аннотация

A new method for the synthesis of dihydroimidazo[1,2-a][1,3,5]triazin-4(6H) -ones via copper(I)-catalyzed hydroamination was developed. In addition, for the first time, iodoalkynes were shown to participate in the copper(I)-catalyzed intramolecular hydroamination reaction with exclusive formation of E-isomers.

Язык оригинала	Английский
Страницы (с-по)	8662-8665
Число страниц	4
Журнал	Journal of Organic Chemistry
Том	75
Номер выпуска	24
DOI	https://doi.org/10.1021/jo1016376
Состояние	Опубликовано - 17 дек 2010
Опубликовано для внешнего пользования	Да

ASJC Scopus subject areas

Organic Chemistry

Доступ к документу

10.1021/jo1016376

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Цитировать

Krasnova, L. B., Hein, J. E., & Fokin, V. V. (2010). Synthesis of 7-aza-5-deazapurine analogues via copper(I)-catalyzed hydroamination of alkynes and 1-iodoalkynes. Journal of Organic Chemistry, 75(24), 8662-8665. https://doi.org/10.1021/jo1016376

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