Synthesis and biological activity of hydrazones of o- and p-hydroxybenzoic acids. Spatial structure of 5-Bromo-2-hydroxybenzylidene-4-hydroxybenzohydrazide

O. A. Nurkenov, Zh B. Satpaeva, I. A. Schepetkin, A. I. Khlebnikov, K. M. Turdybekov, T. M. Seilkhanov, S. D. Fazylov

Результат исследований: Материалы для журналаСтатья

4 Цитирования (Scopus)

Аннотация

A series of hydrazones based on hydrazides of o- and p-hydroxybenzoic acids have been prepared. N-(5-Bromo-2-hydroxybenzylidene)-4-hydroxybenzohydrazide has been studied by X-ray diffraction analysis; its molecule forms hydrogen bond with a solvating ethanol molecule. Biological activity of the synthesized hydrazones towards cathepsin Е and(or) elastase of human neutrophils has been determined.

Язык оригиналаАнглийский
Страницы (с-по)2299-2306
Число страниц8
ЖурналRussian Journal of General Chemistry
Том87
Номер выпуска10
DOI
СостояниеОпубликовано - 1 окт 2017

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ASJC Scopus subject areas

  • Chemistry(all)

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