Synthesis and antitumor activity of 7-(triazol-1-yl)pyrroloallocolchicine derivatives

N. S. Sitnikov, A. V. Sintsov, E. S. Shchegravina, A. Prokop, H. G. Schmalz, V. V. Fokin, A. Yu Fedorov

Результат исследований: Материалы для журнала › Статья

Аннотация

The cycloaddition of acetylene derivatives of azido-substituted pyrroloallocolchicines afforded 7-(triazol-1-yl)pyrroloallocolchicines. The synthesized compounds exhibit considerable cytotoxicity and apoptosis-inducing activity against Nalm 6 human leukemia cells.

Язык оригинала	Английский
Страницы (с-по)	1362-1368
Число страниц	7
Журнал	Russian Chemical Bulletin
Том	64
Номер выпуска	6
DOI	https://doi.org/10.1007/s11172-015-1018-z
Состояние	Опубликовано - 1 июн 2015
Опубликовано для внешнего пользования	Да

ASJC Scopus subject areas

Chemistry(all)

Доступ к документу

10.1007/s11172-015-1018-z

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Цитировать

Sitnikov, N. S., Sintsov, A. V., Shchegravina, E. S., Prokop, A., Schmalz, H. G., Fokin, V. V., & Fedorov, A. Y. (2015). Synthesis and antitumor activity of 7-(triazol-1-yl)pyrroloallocolchicine derivatives. Russian Chemical Bulletin, 64(6), 1362-1368. https://doi.org/10.1007/s11172-015-1018-z

Synthesis and antitumor activity of 7-(triazol-1-yl)pyrroloallocolchicine derivatives. / Sitnikov, N. S.; Sintsov, A. V.; Shchegravina, E. S.; Prokop, A.; Schmalz, H. G.; Fokin, V. V.; Fedorov, A. Yu.

В: Russian Chemical Bulletin, Том 64, № 6, 01.06.2015, стр. 1362-1368.

Результат исследований: Материалы для журнала › Статья

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author = "Sitnikov, {N. S.} and Sintsov, {A. V.} and Shchegravina, {E. S.} and A. Prokop and Schmalz, {H. G.} and Fokin, {V. V.} and Fedorov, {A. Yu}",

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AU - Sitnikov, N. S.

AU - Sintsov, A. V.

AU - Shchegravina, E. S.

AU - Prokop, A.

AU - Schmalz, H. G.

AU - Fokin, V. V.

AU - Fedorov, A. Yu

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KW - antitumor activity

KW - dipolar cycloaddition

KW - triazoles

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