TY - JOUR
T1 - 99mTc-HMPAO-labeled autologous leukocyte SPECT/CT for diagnosis of bacterial endocarditis of the prosthetic pulmonary conduit
T2 - A clinical case
AU - Sazonova, Svetlana Ivanovna
AU - Ilyushenkova, Julia Nikolaevna
AU - Zavadovsky, Konstantin Valer’Evich
AU - Lishmanov, Yuri Borisovich
PY - 2017/1/1
Y1 - 2017/1/1
N2 - In this paper, wepresent a case of bacterial endocarditis of the prostheticpulmonary conduitfoundin a 26-year-oldman. Anechocardiography study around the pulmonary valve showed the presence of a floating mass attached to the wall of the conduit. This formation was thought to be a floating calcific leaflet of the conduit or a developed vegetation of the conduit. Due to the uncertainty of the results, pulmonary multidetector row computed tomography (MDCT) angiography was performed. TheMDCTexamination showed the presence of a floating 4 × 8-mm sized mass in the pulmonary conduit. Taking into account the patient’s complaints, medical history data, and clinical-instrumental examination, myocardial scintigraphy with 99mTc-HMPAO-labelled autologous leukocytes combined with CT (99mTc-HMPAO-SPECT/CT) was performed. Based on overlaying of the scintigraphic images and the MDCT aortography scans, anatomic localization of the pathologic accumulation was found in a projection of the pulmonary valve prosthesis. Surgical intervention, with cardiopulmonary bypass, was performed for replacement of the valve-containing conduit. Pathomorphologic study of the surgical material confirmed the hypothesis of bacterial endocarditis. Therefore, hybrid technologies such as99mTc-HMPAO-SPECT/CT contribute to the earlier and more precise diagnosis of infectious endocarditis, avoiding many errors associated with patient treatment and the development of complications.
AB - In this paper, wepresent a case of bacterial endocarditis of the prostheticpulmonary conduitfoundin a 26-year-oldman. Anechocardiography study around the pulmonary valve showed the presence of a floating mass attached to the wall of the conduit. This formation was thought to be a floating calcific leaflet of the conduit or a developed vegetation of the conduit. Due to the uncertainty of the results, pulmonary multidetector row computed tomography (MDCT) angiography was performed. TheMDCTexamination showed the presence of a floating 4 × 8-mm sized mass in the pulmonary conduit. Taking into account the patient’s complaints, medical history data, and clinical-instrumental examination, myocardial scintigraphy with 99mTc-HMPAO-labelled autologous leukocytes combined with CT (99mTc-HMPAO-SPECT/CT) was performed. Based on overlaying of the scintigraphic images and the MDCT aortography scans, anatomic localization of the pathologic accumulation was found in a projection of the pulmonary valve prosthesis. Surgical intervention, with cardiopulmonary bypass, was performed for replacement of the valve-containing conduit. Pathomorphologic study of the surgical material confirmed the hypothesis of bacterial endocarditis. Therefore, hybrid technologies such as99mTc-HMPAO-SPECT/CT contribute to the earlier and more precise diagnosis of infectious endocarditis, avoiding many errors associated with patient treatment and the development of complications.
KW - Bacterial endocarditis
KW - Inflammation
KW - SPECT/CT
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U2 - 10.5812/iranjradiol.34073
DO - 10.5812/iranjradiol.34073
M3 - Article
AN - SCOPUS:85013404974
VL - 14
JO - Iranian Journal of Radiology
JF - Iranian Journal of Radiology
SN - 1735-1065
IS - 1
M1 - e34073
ER -