Выдержка
An approach to identifying the effects of different groups of antibiotics (tetracyclines, penicillins, cephalosporins) on the vital activity of lactobacilli by fluorimetry is described. The method is based on measurement of the fluorescence intensity of the intracellular metabolite nicotinamide adenine dinucleotide, reduced form (NADH). Different classes of antibiotics were found to have different effects on lactobacilli. Amoxycillin produced no microbial death, while tetracycline and cephazolin had different levels of fatal effects on lactobacilli.
| Язык оригинала | Английский |
|---|---|
| Страницы (с-по) | 262-264 |
| Число страниц | 3 |
| Журнал | Pharmaceutical Chemistry Journal |
| Том | 50 |
| Номер выпуска | 4 |
| DOI | |
| Состояние | Опубликовано - 1 авг 2016 |
Отпечаток
ASJC Scopus subject areas
- Pharmacology
- Drug Discovery
Цитировать
Studies of the Effects of Antibiotics on the Microflora of the Gastrointestinal Tract by Fluorimetry. / Bulycheva, E. V.; Korotkova, E. I.; Timofeeva, E. V.
В: Pharmaceutical Chemistry Journal, Том 50, № 4, 01.08.2016, стр. 262-264.Результат исследований: Материалы для журнала › Статья
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TY - JOUR
T1 - Studies of the Effects of Antibiotics on the Microflora of the Gastrointestinal Tract by Fluorimetry
AU - Bulycheva, E. V.
AU - Korotkova, E. I.
AU - Timofeeva, E. V.
PY - 2016/8/1
Y1 - 2016/8/1
N2 - An approach to identifying the effects of different groups of antibiotics (tetracyclines, penicillins, cephalosporins) on the vital activity of lactobacilli by fluorimetry is described. The method is based on measurement of the fluorescence intensity of the intracellular metabolite nicotinamide adenine dinucleotide, reduced form (NADH). Different classes of antibiotics were found to have different effects on lactobacilli. Amoxycillin produced no microbial death, while tetracycline and cephazolin had different levels of fatal effects on lactobacilli.
AB - An approach to identifying the effects of different groups of antibiotics (tetracyclines, penicillins, cephalosporins) on the vital activity of lactobacilli by fluorimetry is described. The method is based on measurement of the fluorescence intensity of the intracellular metabolite nicotinamide adenine dinucleotide, reduced form (NADH). Different classes of antibiotics were found to have different effects on lactobacilli. Amoxycillin produced no microbial death, while tetracycline and cephazolin had different levels of fatal effects on lactobacilli.
KW - antimicrobial activity
KW - intracellular metabolite
KW - lactobacilli
KW - luminescence analysis
UR - http://www.scopus.com/inward/record.url?scp=84981534326&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84981534326&partnerID=8YFLogxK
U2 - 10.1007/s11094-016-1434-x
DO - 10.1007/s11094-016-1434-x
M3 - Article
AN - SCOPUS:84981534326
VL - 50
SP - 262
EP - 264
JO - Pharmaceutical Chemistry Journal
JF - Pharmaceutical Chemistry Journal
SN - 0091-150X
IS - 4
ER -