Studies of the Effects of Antibiotics on the Microflora of the Gastrointestinal Tract by Fluorimetry

E. V. Bulycheva, E. I. Korotkova, E. V. Timofeeva

Отделение химической инженерии

Результат исследования: Материалы для журнала › Статья

Аннотация

An approach to identifying the effects of different groups of antibiotics (tetracyclines, penicillins, cephalosporins) on the vital activity of lactobacilli by fluorimetry is described. The method is based on measurement of the fluorescence intensity of the intracellular metabolite nicotinamide adenine dinucleotide, reduced form (NADH). Different classes of antibiotics were found to have different effects on lactobacilli. Amoxycillin produced no microbial death, while tetracycline and cephazolin had different levels of fatal effects on lactobacilli.

Язык оригинала	Английский
Страницы (с... по...)	262-264
Количество страниц	3
Журнал	Pharmaceutical Chemistry Journal
Том	50
Номер выпуска	4
DOI	https://doi.org/10.1007/s11094-016-1434-x
Статус публикации	Опубликовано - 1 авг 2016

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ASJC Scopus subject areas

Pharmacology
Drug Discovery

Цитировать

Bulycheva, E. V., Korotkova, E. I., & Timofeeva, E. V. (2016). Studies of the Effects of Antibiotics on the Microflora of the Gastrointestinal Tract by Fluorimetry. Pharmaceutical Chemistry Journal, 50(4), 262-264. https://doi.org/10.1007/s11094-016-1434-x

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Доступ к документу

10.1007/s11094-016-1434-x