[Structural changes of some organs in rats after a single intravenous injection of magnetite nanoparticles].

I. V. Mil'to, I. V. Sukhodolo

    Результат исследования: Материалы для журналаСтатья

    2 Цитирования (Scopus)

    Аннотация

    The aim of this investigation was to study the morphological changes of liver, lung, kidneys and spleen as well as of the cells of mononuclear pahagocyte system in 60 rats 1-40 days after a single intravenous injection of a suspension of magnetite nanoparticles. Moderate hemodynamic disturbances and focal necrotic changes were detected in the hepatic and renal parenchyma. In the lungs and spleen, only hemodynamic disturbances were found. The degree of morphological changes in rat liver, lungs, kidneys and spleen was decreased by day 10. Using Perls histochemical method, the accumulation of nanoparticles was detected in the cells of mononuclear phagocyte system of the organs studied.

    Язык оригиналаАнглийский
    Страницы (с... по...)49-53
    Количество страниц5
    ЖурналMorfologii{combining double inverted breve}a (Saint Petersburg, Russia)
    Том141
    Номер выпуска2
    Статус публикацииОпубликовано - 2012

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    ASJC Scopus subject areas

    • Histology
    • Pathology and Forensic Medicine

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