Radiation-induced reactions in breast cancer patients after breast-conserving surgery with intraoperative and external beam radiotherapy

L. I. Musabaeva, V. A. Lisin, V. V. Velikaia

    Результат исследования: Материалы для журналаСтатья

    4 Цитирования (Scopus)


    The present study is aimed to evaluate the frequency and severity of radiation-induced reactions in patients with stage T1-2N0-1M0 breast cancer, who received intraopeartive radiation therapy (IORT) in combination with external beam radiotherapy (EBRT). A small-size betatron producing 6 MeV electron beam was used for IORT. External beam radiotherapy was performed using Rokus and Theratron machines. Radiotherapy treatment was planned using a specially devised method to ensure acceptable levels of severity and frequency of radiation reactions. The patients were divided into 3 groups: the study (40 patients), control (88) and comparison (50) ones. Radiation-induced skin reactions in the study group ranged from erythema to moist desquamation and edema. Magnetic laser therapy was used to treat radiation-induced injuries. The applied method of estimating the total dose of IORT and EBRT was shown to provide the acceptable levels of severity and frequency of radiation reactions.

    Язык оригиналаАнглийский
    Страницы (с... по...)474-478
    Количество страниц5
    ЖурналRadiatsionnaya Biologiya. Radioekologiya
    Номер выпуска5
    Статус публикацииОпубликовано - 1 сен 2014


    ASJC Scopus subject areas

    • Medicine(all)