Preparation of biocompatible composites based on poly-L-lactide/ hydroxyapatite and investigation of their anti-inflammatory activity

Yelena Shapovalova, Daria Lytkina, Liudmila Rasskazova, Ilya Zhuk, Alexandru Gudima, Anatoly Filimoshkin, Natalya Korotchenko, Irina Kurzina, Julia Kzhyshkowska

    Результат исследований: Материалы для книги/типы отчетовМатериалы для конференции

    4 Цитирования (Scopus)

    Выдержка

    Relevance of the work is due to the need for new materials that are used in medicine as a substitute for natural bone tissue injuries, fractures, etc. The aim of the work is to obtain composites with improved biocompatible properties based on poly-L-lactide (PLA) and hydroxyapatite (HA) and to perform pilot analysis of interaction PLA, HA, composite PLA-HA with primary human monocytes-derived macrophages in vitro. The pilot experiments using human primary monocytes cultivated on the surface of the samples demonstrated that PLA-HA can stimulate release of antiinflammatory cytokines that indicates the presence of potential anti-inflammatory properties of the composites.

    Язык оригиналаАнглийский
    Название основной публикацииMultifunctional Materials
    Подзаголовок основной публикацииDevelopment and Application
    ИздательTrans Tech Publications Ltd
    Страницы475-480
    Число страниц6
    ISBN (печатное издание)9783038357292
    DOI
    СостояниеОпубликовано - 1 янв 2016
    Событие12th International Conference on Prospects of Fundamental Sciences Development, PFSD 2015 - Tomsk, Российская Федерация
    Продолжительность: 21 апр 201524 апр 2015

    Серия публикаций

    НазваниеKey Engineering Materials
    Том683
    ISSN (печатное издание)1013-9826

    Конференция

    Конференция12th International Conference on Prospects of Fundamental Sciences Development, PFSD 2015
    СтранаРоссийская Федерация
    ГородTomsk
    Период21.4.1524.4.15

    Отпечаток

    Hydroxyapatite
    Anti-Inflammatory Agents
    Composite materials
    Macrophages
    Medicine
    Bone
    Tissue
    Cytokines
    hydroxyapatite-polylactide
    Experiments

    ASJC Scopus subject areas

    • Materials Science(all)
    • Mechanics of Materials
    • Mechanical Engineering

    Цитировать

    Shapovalova, Y., Lytkina, D., Rasskazova, L., Zhuk, I., Gudima, A., Filimoshkin, A., ... Kzhyshkowska, J. (2016). Preparation of biocompatible composites based on poly-L-lactide/ hydroxyapatite and investigation of their anti-inflammatory activity. В Multifunctional Materials: Development and Application (стр. 475-480). (Key Engineering Materials; Том 683). Trans Tech Publications Ltd. https://doi.org/10.4028/www.scientific.net/KEM.683.475

    Preparation of biocompatible composites based on poly-L-lactide/ hydroxyapatite and investigation of their anti-inflammatory activity. / Shapovalova, Yelena; Lytkina, Daria; Rasskazova, Liudmila; Zhuk, Ilya; Gudima, Alexandru; Filimoshkin, Anatoly; Korotchenko, Natalya; Kurzina, Irina; Kzhyshkowska, Julia.

    Multifunctional Materials: Development and Application. Trans Tech Publications Ltd, 2016. стр. 475-480 (Key Engineering Materials; Том 683).

    Результат исследований: Материалы для книги/типы отчетовМатериалы для конференции

    Shapovalova, Y, Lytkina, D, Rasskazova, L, Zhuk, I, Gudima, A, Filimoshkin, A, Korotchenko, N, Kurzina, I & Kzhyshkowska, J 2016, Preparation of biocompatible composites based on poly-L-lactide/ hydroxyapatite and investigation of their anti-inflammatory activity. в Multifunctional Materials: Development and Application. Key Engineering Materials, том. 683, Trans Tech Publications Ltd, стр. 475-480, Tomsk, Российская Федерация, 21.4.15. https://doi.org/10.4028/www.scientific.net/KEM.683.475
    Shapovalova Y, Lytkina D, Rasskazova L, Zhuk I, Gudima A, Filimoshkin A и соавт. Preparation of biocompatible composites based on poly-L-lactide/ hydroxyapatite and investigation of their anti-inflammatory activity. В Multifunctional Materials: Development and Application. Trans Tech Publications Ltd. 2016. стр. 475-480. (Key Engineering Materials). https://doi.org/10.4028/www.scientific.net/KEM.683.475
    Shapovalova, Yelena ; Lytkina, Daria ; Rasskazova, Liudmila ; Zhuk, Ilya ; Gudima, Alexandru ; Filimoshkin, Anatoly ; Korotchenko, Natalya ; Kurzina, Irina ; Kzhyshkowska, Julia. / Preparation of biocompatible composites based on poly-L-lactide/ hydroxyapatite and investigation of their anti-inflammatory activity. Multifunctional Materials: Development and Application. Trans Tech Publications Ltd, 2016. стр. 475-480 (Key Engineering Materials).
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    AU - Rasskazova, Liudmila

    AU - Zhuk, Ilya

    AU - Gudima, Alexandru

    AU - Filimoshkin, Anatoly

    AU - Korotchenko, Natalya

    AU - Kurzina, Irina

    AU - Kzhyshkowska, Julia

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