Preparation of a silicate-containing hydroxyapatite-based coating by magnetron sputtering: structure and osteoblast-like MG63 cells in vitro study: Structure and osteoblast-like MG63 cells in vitro study

M. A. Surmeneva, A. Kovtun, A. Peetsch, S. N. Goroja, A. A. Sharonova, V. F. Pichugin, I. Y. Grubova, A. A. Ivanova, A. D. Teresov, Nikolay Nikolaevich Koval, V. Buck, A. Wittmar, M. Ulbricht, O. Prymak, M. Epple, R. A. Surmenev

Результат исследований: Материалы для журналаСтатья

34 Цитирования (Scopus)

Аннотация

Silicate-containing hydroxyapatite-based coatings with different structure and calcium/phosphate ratios were prepared by radio-frequency magnetron sputtering on silicon and titanium substrates, respectively. Scanning electron microscopy, X-ray diffraction and IR spectroscopy were used to investigate the effect of the substrate bias on the properties of the silicate-containing hydroxyapatite-based coatings. The deposition rate, composition, and microstructure of the deposited coatings were all controlled by changing the bias voltage from grounded (0 V) to -50 and -100 V. The biocompatibility was assessed by cell culture with human osteoblast-like cells (MG-63 cell line), showing a good biocompatibility and cell growth on the substrates.

Язык оригиналаАнглийский
Страницы (с-по)11240-11246
Число страниц7
ЖурналRSC Advances
Том3
Номер выпуска28
DOI
СостояниеОпубликовано - 28 июл 2013

ASJC Scopus subject areas

  • Chemical Engineering(all)
  • Chemistry(all)

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