Porphyrin‑silver nanoparticles hybrids: Synthesis, characterization and antibacterial activity

R. Elashnikov, M. Radocha, I. Panov, S. Rimpelova, P. Ulbrich, A. Michalcova, V. Svorcik, O. Lyutakov

Результат исследований: Материалы для журналаСтатья

1 цитирование (Scopus)

Выдержка

The preparation of light-activated hybrid antibacterial agent combining the porphyrin molecules, bound to the silver nanoparticles (AgNPs) surface is reported. AgNPs were synthesized by N-methyl-2-pyrrolidone-initiated reduction without additional reducing agents. The chemical structure of protoporphyrin IX was modified with the aim to introduce thiol groups. The size distribution and shape features of AgNPs were checked using TEM and HRTEM microscopies. The introduction of thiol groups into the porphyrin was proved by IR spectroscopy. The AgNPs-porphyrin binding was performed in solution and confirmed by fluorescence quenching, Raman spectroscopy and energy-filtered transmission electron microscopy (EFTEM). The antibacterial tests were performed against S. epidermidis and E. coli upon to LED illumination and in the dark. The synergetic effect of AgNPs and porphyrin as well as light activation of the created antibacterial conjugates were observed.

Язык оригиналаАнглийский
Страницы (с-по)192-199
Число страниц8
ЖурналMaterials Science and Engineering C
Том102
DOI
СостояниеОпубликовано - 1 сен 2019
Опубликовано для внешнего пользованияДа

Отпечаток

Porphyrins
porphyrins
Nanoparticles
nanoparticles
synthesis
Sulfhydryl Compounds
thiols
Transmission electron microscopy
Bactericides
transmission electron microscopy
Reducing Agents
Reducing agents
Silver
Escherichia coli
Light emitting diodes
Raman spectroscopy
Infrared spectroscopy
Quenching
Microscopic examination
light emitting diodes

ASJC Scopus subject areas

  • Materials Science(all)
  • Condensed Matter Physics
  • Mechanics of Materials
  • Mechanical Engineering

Цитировать

Porphyrin‑silver nanoparticles hybrids : Synthesis, characterization and antibacterial activity. / Elashnikov, R.; Radocha, M.; Panov, I.; Rimpelova, S.; Ulbrich, P.; Michalcova, A.; Svorcik, V.; Lyutakov, O.

В: Materials Science and Engineering C, Том 102, 01.09.2019, стр. 192-199.

Результат исследований: Материалы для журналаСтатья

Elashnikov, R, Radocha, M, Panov, I, Rimpelova, S, Ulbrich, P, Michalcova, A, Svorcik, V & Lyutakov, O 2019, 'Porphyrin‑silver nanoparticles hybrids: Synthesis, characterization and antibacterial activity', Materials Science and Engineering C, том. 102, стр. 192-199. https://doi.org/10.1016/j.msec.2019.04.029
Elashnikov R, Radocha M, Panov I, Rimpelova S, Ulbrich P, Michalcova A и соавт. Porphyrin‑silver nanoparticles hybrids: Synthesis, characterization and antibacterial activity. Materials Science and Engineering C. 2019 Сент. 1;102:192-199. https://doi.org/10.1016/j.msec.2019.04.029
Elashnikov, R. ; Radocha, M. ; Panov, I. ; Rimpelova, S. ; Ulbrich, P. ; Michalcova, A. ; Svorcik, V. ; Lyutakov, O. / Porphyrin‑silver nanoparticles hybrids : Synthesis, characterization and antibacterial activity. В: Materials Science and Engineering C. 2019 ; Том 102. стр. 192-199.
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