Polylactic acid properties after steam sterilization and possibility of its using as a corneal implant

Результат исследований: Материалы для книги/типы отчетовМатериалы для конференции

Аннотация

The purpose of this research is the study of the influence of thin polylactic acid (PLA) films implantation on the corneal morphology in vivo experiment. Studies were performed on 8 pubescent female Sylvilagus bachmani rabbits. PLA films were implanted into the anterior chamber of one animal eye. The feedstock for the films was obtained by dissolving PLA in the chloroform. Before the implantation PLA films were sterilized. The overall duration of the in vivo experiment comprised 21 days. Such methods as visual check, photographic registration, non-contact ocular tonometry and optical coherent tomography of cornea were also used in course of the experiment. Sampling was performed on day 21 after the start of the experiment for morphology studying. Results showed that the implantation of the PLA films into the anterior chamber of eye does not induce an inflammatory reaction and does not increase an intraocular pressure. The study showed the possibility of PLA films using as a corneal implant.

Язык оригиналаАнглийский
Название основной публикацииProceedings of the International Conference on Advanced Materials with Hierarchical Structure for New Technologies and Reliable Structures 2019
РедакторыVictor E. Panin, Sergey G. Psakhie, Vasily M. Fomin
ИздательAmerican Institute of Physics Inc.
ISBN (электронное издание)9780735419124
DOI
СостояниеОпубликовано - 19 ноя 2019
СобытиеInternational Conference on Advanced Materials with Hierarchical Structure for New Technologies and Reliable Structures 2019 - Tomsk, Российская Федерация
Продолжительность: 1 окт 20195 окт 2019

Серия публикаций

НазваниеAIP Conference Proceedings
Том2167
ISSN (печатное издание)0094-243X
ISSN (электронное издание)1551-7616

Конференция

КонференцияInternational Conference on Advanced Materials with Hierarchical Structure for New Technologies and Reliable Structures 2019
СтранаРоссийская Федерация
ГородTomsk
Период1.10.195.10.19

ASJC Scopus subject areas

  • Physics and Astronomy(all)

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  • Цитировать

    Filippova, E. O., & Ivanova, N. M. (2019). Polylactic acid properties after steam sterilization and possibility of its using as a corneal implant. В V. E. Panin, S. G. Psakhie, & V. M. Fomin (Ред.), Proceedings of the International Conference on Advanced Materials with Hierarchical Structure for New Technologies and Reliable Structures 2019 [020104] (AIP Conference Proceedings; Том 2167). American Institute of Physics Inc.. https://doi.org/10.1063/1.5131971