Polyhedral boron compounds as potential linkers for attachment of radiohalogens to targeting proteins and peptides. A review

Vladimir Tolmachev, Stefan Sjöberg

Результат исследований: Материалы для журналаОбзорная статьярецензирование

46 Цитирования (Scopus)

Аннотация

Polyhedral boron clusters (PBC) are three-dimensional inorganic aromatic systems. Some of them can easily be halogenated, and the halogen-boron bond in such systems is very strong. We consider the use of PBC as linkers for attachment of radioactive halogen isotopes to tumor-targeting proteins and peptides. In this review the major preconditions for such applications, such as biological considerations, knowledge concerning coupling chemistry and radiolabeling of PBC, are described. A review with 90 references.

Язык оригиналаАнглийский
Страницы (с-по)913-935
Число страниц23
ЖурналCollection of Czechoslovak Chemical Communications
Том67
Номер выпуска7
DOI
СостояниеОпубликовано - 1 июл 2002
Опубликовано для внешнего пользованияДа

ASJC Scopus subject areas

  • Chemistry(all)

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