Polarographic and voltammetric determination of genotoxic nitro derivatives of quinoline using mercury electrodes

Vlastimil Vyskočil, Ivan Jiránek, Aleš Daňhel, Jiří Zima, Jiří Barek, Joseph Wang, Karolina Pecková

Результат исследований: Материалы для журналаСтатья

4 Цитирования (Scopus)

Выдержка

Electrochemical behavior of genotoxic nitro derivatives of quinoline, namely 5-nitroquinoline (5-NQ), 6-nitroquinoline (6-NQ) and 8-nitroquinoline (8-NQ), was investigated by DC tast polarography (DCTP) and differential pulse polarography (DPP), both at a classical dropping mercury electrode (DME), and by differential pulse voltammetry (DPV) and adsorptive stripping differential pulse voltammetry (AdSDPV), both at a miniaturized hanging mercury drop minielectrode (HMDmE), in buffered aqueous (for 5-NQ) or aqueous-methanolic (for 6-NQ and 8-NQ) solutions. Optimum conditions were found for the determination of 5-NQ, 6-NQ and 8-NQ by DCTP at DME (with limits of quantification, L Q ≈ 9 × 10 -7, 3 × 10 -7 and 2 × 10 -6 mol l -1, respectively), by DPP at DME (L Q ≈ 1 × 10 -8, 9 × 10 -8 and 1 × 10 -7 mol l -1, respectively), by DPV at HMDmE (L Q ≈ 2 × 10 -8, 1 × 10 -7 and 1 × 10 -7 mol l -1, respectively), and by AdSDPV at HMDmE (L Q ≈ 1 × 10 -8 mol l -1 for 8-NQ; an attempt at increasing the sensitivity using AdSDPV at HMDmE was not successful for 5-NQ and 6-NQ). Practical applicability of the developed methods was verified on the direct determination of the studied compounds in model samples of drinking and river water in submicromolar concentrations and on the determination in model samples of drinking and river water using preliminary separation and preconcentration by solid phase extraction (SPE) in nanomolar concentrations.

Язык оригиналаАнглийский
Страницы (с-по)1991-2004
Число страниц14
ЖурналCollection of Czechoslovak Chemical Communications
Том76
Номер выпуска12
DOI
СостояниеОпубликовано - 1 дек 2011
Опубликовано для внешнего пользованияДа

Отпечаток

Nitroquinolines
Mercury
Derivatives
Voltammetry
Polarographic analysis
Electrodes
Rivers
quinoline
Water

ASJC Scopus subject areas

  • Chemistry(all)

Цитировать

Polarographic and voltammetric determination of genotoxic nitro derivatives of quinoline using mercury electrodes. / Vyskočil, Vlastimil; Jiránek, Ivan; Daňhel, Aleš; Zima, Jiří; Barek, Jiří; Wang, Joseph; Pecková, Karolina.

В: Collection of Czechoslovak Chemical Communications, Том 76, № 12, 01.12.2011, стр. 1991-2004.

Результат исследований: Материалы для журналаСтатья

Vyskočil, Vlastimil ; Jiránek, Ivan ; Daňhel, Aleš ; Zima, Jiří ; Barek, Jiří ; Wang, Joseph ; Pecková, Karolina. / Polarographic and voltammetric determination of genotoxic nitro derivatives of quinoline using mercury electrodes. В: Collection of Czechoslovak Chemical Communications. 2011 ; Том 76, № 12. стр. 1991-2004.
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abstract = "Electrochemical behavior of genotoxic nitro derivatives of quinoline, namely 5-nitroquinoline (5-NQ), 6-nitroquinoline (6-NQ) and 8-nitroquinoline (8-NQ), was investigated by DC tast polarography (DCTP) and differential pulse polarography (DPP), both at a classical dropping mercury electrode (DME), and by differential pulse voltammetry (DPV) and adsorptive stripping differential pulse voltammetry (AdSDPV), both at a miniaturized hanging mercury drop minielectrode (HMDmE), in buffered aqueous (for 5-NQ) or aqueous-methanolic (for 6-NQ and 8-NQ) solutions. Optimum conditions were found for the determination of 5-NQ, 6-NQ and 8-NQ by DCTP at DME (with limits of quantification, L Q ≈ 9 × 10 -7, 3 × 10 -7 and 2 × 10 -6 mol l -1, respectively), by DPP at DME (L Q ≈ 1 × 10 -8, 9 × 10 -8 and 1 × 10 -7 mol l -1, respectively), by DPV at HMDmE (L Q ≈ 2 × 10 -8, 1 × 10 -7 and 1 × 10 -7 mol l -1, respectively), and by AdSDPV at HMDmE (L Q ≈ 1 × 10 -8 mol l -1 for 8-NQ; an attempt at increasing the sensitivity using AdSDPV at HMDmE was not successful for 5-NQ and 6-NQ). Practical applicability of the developed methods was verified on the direct determination of the studied compounds in model samples of drinking and river water in submicromolar concentrations and on the determination in model samples of drinking and river water using preliminary separation and preconcentration by solid phase extraction (SPE) in nanomolar concentrations.",
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T1 - Polarographic and voltammetric determination of genotoxic nitro derivatives of quinoline using mercury electrodes

AU - Vyskočil, Vlastimil

AU - Jiránek, Ivan

AU - Daňhel, Aleš

AU - Zima, Jiří

AU - Barek, Jiří

AU - Wang, Joseph

AU - Pecková, Karolina

PY - 2011/12/1

Y1 - 2011/12/1

N2 - Electrochemical behavior of genotoxic nitro derivatives of quinoline, namely 5-nitroquinoline (5-NQ), 6-nitroquinoline (6-NQ) and 8-nitroquinoline (8-NQ), was investigated by DC tast polarography (DCTP) and differential pulse polarography (DPP), both at a classical dropping mercury electrode (DME), and by differential pulse voltammetry (DPV) and adsorptive stripping differential pulse voltammetry (AdSDPV), both at a miniaturized hanging mercury drop minielectrode (HMDmE), in buffered aqueous (for 5-NQ) or aqueous-methanolic (for 6-NQ and 8-NQ) solutions. Optimum conditions were found for the determination of 5-NQ, 6-NQ and 8-NQ by DCTP at DME (with limits of quantification, L Q ≈ 9 × 10 -7, 3 × 10 -7 and 2 × 10 -6 mol l -1, respectively), by DPP at DME (L Q ≈ 1 × 10 -8, 9 × 10 -8 and 1 × 10 -7 mol l -1, respectively), by DPV at HMDmE (L Q ≈ 2 × 10 -8, 1 × 10 -7 and 1 × 10 -7 mol l -1, respectively), and by AdSDPV at HMDmE (L Q ≈ 1 × 10 -8 mol l -1 for 8-NQ; an attempt at increasing the sensitivity using AdSDPV at HMDmE was not successful for 5-NQ and 6-NQ). Practical applicability of the developed methods was verified on the direct determination of the studied compounds in model samples of drinking and river water in submicromolar concentrations and on the determination in model samples of drinking and river water using preliminary separation and preconcentration by solid phase extraction (SPE) in nanomolar concentrations.

AB - Electrochemical behavior of genotoxic nitro derivatives of quinoline, namely 5-nitroquinoline (5-NQ), 6-nitroquinoline (6-NQ) and 8-nitroquinoline (8-NQ), was investigated by DC tast polarography (DCTP) and differential pulse polarography (DPP), both at a classical dropping mercury electrode (DME), and by differential pulse voltammetry (DPV) and adsorptive stripping differential pulse voltammetry (AdSDPV), both at a miniaturized hanging mercury drop minielectrode (HMDmE), in buffered aqueous (for 5-NQ) or aqueous-methanolic (for 6-NQ and 8-NQ) solutions. Optimum conditions were found for the determination of 5-NQ, 6-NQ and 8-NQ by DCTP at DME (with limits of quantification, L Q ≈ 9 × 10 -7, 3 × 10 -7 and 2 × 10 -6 mol l -1, respectively), by DPP at DME (L Q ≈ 1 × 10 -8, 9 × 10 -8 and 1 × 10 -7 mol l -1, respectively), by DPV at HMDmE (L Q ≈ 2 × 10 -8, 1 × 10 -7 and 1 × 10 -7 mol l -1, respectively), and by AdSDPV at HMDmE (L Q ≈ 1 × 10 -8 mol l -1 for 8-NQ; an attempt at increasing the sensitivity using AdSDPV at HMDmE was not successful for 5-NQ and 6-NQ). Practical applicability of the developed methods was verified on the direct determination of the studied compounds in model samples of drinking and river water in submicromolar concentrations and on the determination in model samples of drinking and river water using preliminary separation and preconcentration by solid phase extraction (SPE) in nanomolar concentrations.

KW - 5-Nitroquinoline

KW - 6-Nitroquinoline

KW - 8-Nitroquinoline

KW - Analytical methods

KW - Electrochemistry

KW - Mercury electrodes

KW - Polarography

KW - Solid phase extraction

KW - Spiked water samples

KW - Voltammetry

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