Peculiarities of adrenergic regulation of smooth muscles in rabbit pulmonary arteries

L. V. Kapilevich, A. V. Nosarev, E. Yu D'yakova, I. V. Kovalev, M. B. Baskakov, Yana Jonovna Anfinogenova, M. A. Medvedev

Результат исследований: Материалы для журналаСтатья

1 цитирование (Scopus)

Выдержка

Muscle tension recording was used to study adrenergic contractile reactions of pulmonary artery smooth muscles in rabbits. Stimulation of α-adrenoceptors induced contraction of pulmonary artery smooth muscle cells. Endothelium partially inhibited the contractile effect of α-adrenoceptor agonists. Activation of smooth muscle β-adrenoceptors in pulmonary arteries produced a dual dose-dependent effect (relaxation at agonist concentrations of 10 nM-1 μM and contraction at concentrations above 10 μM). The contractile effect of β-adrenoceptor activation in smooth muscle cells is a specific feature of pulmonary arteries probably related to peculiarities of cAMP-signaling in these cells.

Язык оригиналаАнглийский
Страницы (с-по)214-216
Число страниц3
ЖурналBulletin of Experimental Biology and Medicine
Том133
Номер выпуска3
DOI
СостояниеОпубликовано - авг 2002
Опубликовано для внешнего пользованияДа

Отпечаток

Adrenergic Agents
Adrenergic Receptors
Pulmonary Artery
Smooth Muscle
Muscle
Rabbits
Smooth Muscle Myocytes
Muscle Tonus
Chemical activation
Cells
Endothelium

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Цитировать

Peculiarities of adrenergic regulation of smooth muscles in rabbit pulmonary arteries. / Kapilevich, L. V.; Nosarev, A. V.; D'yakova, E. Yu; Kovalev, I. V.; Baskakov, M. B.; Anfinogenova, Yana Jonovna; Medvedev, M. A.

В: Bulletin of Experimental Biology and Medicine, Том 133, № 3, 08.2002, стр. 214-216.

Результат исследований: Материалы для журналаСтатья

Kapilevich, L. V. ; Nosarev, A. V. ; D'yakova, E. Yu ; Kovalev, I. V. ; Baskakov, M. B. ; Anfinogenova, Yana Jonovna ; Medvedev, M. A. / Peculiarities of adrenergic regulation of smooth muscles in rabbit pulmonary arteries. В: Bulletin of Experimental Biology and Medicine. 2002 ; Том 133, № 3. стр. 214-216.
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AU - Nosarev, A. V.

AU - D'yakova, E. Yu

AU - Kovalev, I. V.

AU - Baskakov, M. B.

AU - Anfinogenova, Yana Jonovna

AU - Medvedev, M. A.

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