Oxidative Cycloaddition of Aldoximes with Maleimides using Catalytic Hydroxy(aryl)iodonium Species

Akira Yoshimura, Khiem C. Nguyen, Gregory T. Rohde, Akio Saito, Mekhman S. Yusubov, Viktor V. Zhdankin

Результат исследований: Материалы для журналаСтатья

14 Цитирования (Scopus)

Аннотация

A mild catalytic procedure for the efficient oxidative cyclization of aldoximes with maleimides mediated by hypervalent iodine(III) active species has been developed. This catalytic cyclization affords the corresponding pyrrolo-isoxazole products in generally good yields. The catalytic cycle involves active hydroxy(aryl)iodonium species generated in situ from 2-iodobenzoic acid as precatalyst and m-chloroperoxybenzoic acid (m-CPBA) as terminal oxidant in the presence of trifluoromethanesulfonic acid. The presence of active hydroxy(aryl)iodonium species in this reaction has been confirmed by ESI-mass spectrometry and1H NMR spectroscopy. (Figure presented.) .

Язык оригиналаАнглийский
Страницы (с-по)2340-2344
Число страниц5
ЖурналAdvanced Synthesis and Catalysis
Том358
Номер выпуска14
DOI
СостояниеОпубликовано - 1 янв 2016

ASJC Scopus subject areas

  • Catalysis
  • Organic Chemistry

Fingerprint Подробные сведения о темах исследования «Oxidative Cycloaddition of Aldoximes with Maleimides using Catalytic Hydroxy(aryl)iodonium Species». Вместе они формируют уникальный семантический отпечаток (fingerprint).

  • Цитировать