Nonwoven polylactide scaffolds obtained by solution blow spinning and the in vitro degradation dynamics

Sergei Tverdokhlebov, Ksenia Sergeevna Stankevich, Evgeny Bolbasov, Igor Albertovich Khlusov, Irina Kulagina, Konstantin Zaitsev

Результат исследований: Материалы для книги/типы отчетовМатериалы для конференции

4 Цитирования (Scopus)

Аннотация

The solution blow spinning is presented as a method of obtaining tissue engineering scaffolds. The different forming modes were used and the optimum experimental conditions were found. It is shown that nonwoven polylactide scaffolds with required surface morphology can be obtained. These samples were studied in case of biodegradation in simulation body fluid. It was found that during scaffold dissolution the pH of the solution changes insignificantly (6.85) despite the exponential increase of the monomers of lactic acid. The calcium and phosphorus ion exchange between the scaffold and solution was observed in the surface and bulk of the material what makes possible to use scaffolds for regenerative medicine.

Язык оригиналаАнглийский
Название основной публикацииNanomaterials for Structural, Functional and Biomedical Applications
Страницы257-262
Число страниц6
DOI
СостояниеОпубликовано - 15 янв 2014
СобытиеRussian-German Forum on Nanotechnology - Tomsk, Российская Федерация
Продолжительность: 21 мая 201324 мая 2013

Серия публикаций

НазваниеAdvanced Materials Research
Том872
ISSN (печатное издание)1022-6680

Другое

ДругоеRussian-German Forum on Nanotechnology
СтранаРоссийская Федерация
ГородTomsk
Период21.5.1324.5.13

ASJC Scopus subject areas

  • Engineering(all)

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