Myocardium perfusion scintigraphy in evaluation of endovascular treatment results of coronary artery disease

Yu B. Lishmanov, J. V. Vesoina, E. V. Rybalchenko, A. L. Krylov

Результат исследований: Материалы для журналаСтатья

Выдержка

Purpose: To determine abilities and principal features of prospective scintigraphic evaluation of endovascular treatment results of coronary artery disease (CAD) using thallium-199 perfusion single-photon emission computed tomography. Material and methods: Forty CAD patients were investigated by perfusion scintigraphy before and 2-3 weeks, 3-6 months and 1-2 years after coronary artery stenting. The character and size of perfusion defects and presence of the reverse radionuclide redistribution phenomenon were estimated. Results: The coronary stenting almost results to the 80 % decrease of mean size of transitory ischemic zones. The presence of reversible perfusion defects after operation was bound up with the incomplete revascularization or with X-syndrome. At later time periods of the observation, the unfavorable course of coronary insufficiency was due to coronary artery restenosis. Mean value of persistent perfusion defects has not changed after endovascular treatment, but 11 patients have demonstrated disappearance or volume decrease of stable ischemic zones at early and late postoperative period, that has testified to myocardial viability. In group of patients with rapid wash-out of thallium ("reverse redistribution" (RR)) there was the occurrence of new reversible and stable perfusion defects in projection of previous existence of RR. The condition of microcirculation of the heart muscle has not undergo remarkable changes in the group of patients without RR. Conclusion: Myocardium thallium-199 chloride perfusion scintigraphy is the objective method for evaluation of coronary stenting results and restenosis diagnostics. It allows to determine hibernating myocardium in CAD patients and discover unfavorable scintigraphy predictors for possible cardiovascular events.

Язык оригиналаАнглийский
Страницы (с-по)45-53
Число страниц9
ЖурналMeditsinskaya Radiologiya I Radiatsionnaya Bezopasnost'
Том49
Номер выпуска4
СостояниеОпубликовано - 2004

Отпечаток

Thallium
Defects
Single photon emission computed tomography
Microcirculation
Radioisotopes
Muscle

ASJC Scopus subject areas

  • Nuclear Energy and Engineering

Цитировать

Myocardium perfusion scintigraphy in evaluation of endovascular treatment results of coronary artery disease. / Lishmanov, Yu B.; Vesoina, J. V.; Rybalchenko, E. V.; Krylov, A. L.

В: Meditsinskaya Radiologiya I Radiatsionnaya Bezopasnost', Том 49, № 4, 2004, стр. 45-53.

Результат исследований: Материалы для журналаСтатья

@article{635c7023bbdd40a08c3467fbd90dc59e,
title = "Myocardium perfusion scintigraphy in evaluation of endovascular treatment results of coronary artery disease",
abstract = "Purpose: To determine abilities and principal features of prospective scintigraphic evaluation of endovascular treatment results of coronary artery disease (CAD) using thallium-199 perfusion single-photon emission computed tomography. Material and methods: Forty CAD patients were investigated by perfusion scintigraphy before and 2-3 weeks, 3-6 months and 1-2 years after coronary artery stenting. The character and size of perfusion defects and presence of the reverse radionuclide redistribution phenomenon were estimated. Results: The coronary stenting almost results to the 80 {\%} decrease of mean size of transitory ischemic zones. The presence of reversible perfusion defects after operation was bound up with the incomplete revascularization or with X-syndrome. At later time periods of the observation, the unfavorable course of coronary insufficiency was due to coronary artery restenosis. Mean value of persistent perfusion defects has not changed after endovascular treatment, but 11 patients have demonstrated disappearance or volume decrease of stable ischemic zones at early and late postoperative period, that has testified to myocardial viability. In group of patients with rapid wash-out of thallium ({"}reverse redistribution{"} (RR)) there was the occurrence of new reversible and stable perfusion defects in projection of previous existence of RR. The condition of microcirculation of the heart muscle has not undergo remarkable changes in the group of patients without RR. Conclusion: Myocardium thallium-199 chloride perfusion scintigraphy is the objective method for evaluation of coronary stenting results and restenosis diagnostics. It allows to determine hibernating myocardium in CAD patients and discover unfavorable scintigraphy predictors for possible cardiovascular events.",
keywords = "Balloon angioplasty, Myocardium perfusion scintigraphy, Reverse redistribution of thallium, Stenting of coronary arteries",
author = "Lishmanov, {Yu B.} and Vesoina, {J. V.} and Rybalchenko, {E. V.} and Krylov, {A. L.}",
year = "2004",
language = "English",
volume = "49",
pages = "45--53",
journal = "Meditsinskaya Radiologiya I Radiatsionnaya Bezopasnost'",
issn = "0025-8334",
publisher = "Izdatel'sto Radekon",
number = "4",

}

TY - JOUR

T1 - Myocardium perfusion scintigraphy in evaluation of endovascular treatment results of coronary artery disease

AU - Lishmanov, Yu B.

AU - Vesoina, J. V.

AU - Rybalchenko, E. V.

AU - Krylov, A. L.

PY - 2004

Y1 - 2004

N2 - Purpose: To determine abilities and principal features of prospective scintigraphic evaluation of endovascular treatment results of coronary artery disease (CAD) using thallium-199 perfusion single-photon emission computed tomography. Material and methods: Forty CAD patients were investigated by perfusion scintigraphy before and 2-3 weeks, 3-6 months and 1-2 years after coronary artery stenting. The character and size of perfusion defects and presence of the reverse radionuclide redistribution phenomenon were estimated. Results: The coronary stenting almost results to the 80 % decrease of mean size of transitory ischemic zones. The presence of reversible perfusion defects after operation was bound up with the incomplete revascularization or with X-syndrome. At later time periods of the observation, the unfavorable course of coronary insufficiency was due to coronary artery restenosis. Mean value of persistent perfusion defects has not changed after endovascular treatment, but 11 patients have demonstrated disappearance or volume decrease of stable ischemic zones at early and late postoperative period, that has testified to myocardial viability. In group of patients with rapid wash-out of thallium ("reverse redistribution" (RR)) there was the occurrence of new reversible and stable perfusion defects in projection of previous existence of RR. The condition of microcirculation of the heart muscle has not undergo remarkable changes in the group of patients without RR. Conclusion: Myocardium thallium-199 chloride perfusion scintigraphy is the objective method for evaluation of coronary stenting results and restenosis diagnostics. It allows to determine hibernating myocardium in CAD patients and discover unfavorable scintigraphy predictors for possible cardiovascular events.

AB - Purpose: To determine abilities and principal features of prospective scintigraphic evaluation of endovascular treatment results of coronary artery disease (CAD) using thallium-199 perfusion single-photon emission computed tomography. Material and methods: Forty CAD patients were investigated by perfusion scintigraphy before and 2-3 weeks, 3-6 months and 1-2 years after coronary artery stenting. The character and size of perfusion defects and presence of the reverse radionuclide redistribution phenomenon were estimated. Results: The coronary stenting almost results to the 80 % decrease of mean size of transitory ischemic zones. The presence of reversible perfusion defects after operation was bound up with the incomplete revascularization or with X-syndrome. At later time periods of the observation, the unfavorable course of coronary insufficiency was due to coronary artery restenosis. Mean value of persistent perfusion defects has not changed after endovascular treatment, but 11 patients have demonstrated disappearance or volume decrease of stable ischemic zones at early and late postoperative period, that has testified to myocardial viability. In group of patients with rapid wash-out of thallium ("reverse redistribution" (RR)) there was the occurrence of new reversible and stable perfusion defects in projection of previous existence of RR. The condition of microcirculation of the heart muscle has not undergo remarkable changes in the group of patients without RR. Conclusion: Myocardium thallium-199 chloride perfusion scintigraphy is the objective method for evaluation of coronary stenting results and restenosis diagnostics. It allows to determine hibernating myocardium in CAD patients and discover unfavorable scintigraphy predictors for possible cardiovascular events.

KW - Balloon angioplasty

KW - Myocardium perfusion scintigraphy

KW - Reverse redistribution of thallium

KW - Stenting of coronary arteries

UR - http://www.scopus.com/inward/record.url?scp=5644244364&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=5644244364&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:5644244364

VL - 49

SP - 45

EP - 53

JO - Meditsinskaya Radiologiya I Radiatsionnaya Bezopasnost'

JF - Meditsinskaya Radiologiya I Radiatsionnaya Bezopasnost'

SN - 0025-8334

IS - 4

ER -