Lithium-based antioxidants: Electrochemical properties and influence on immune cells

Результат исследований: Материалы для журналаСтатья

6 Цитирования (Scopus)

Выдержка

Introduction: Lithium salts are known as effective psychotropic medicine for treatment bipolar disorder and may be used to treat alcoholism, schizoaffective disorders, and cluster headaches. The antioxidant activity and immunomodulatory effects of prospective lithium compounds have been investigated in this work. Materials and Methods: The antioxidant properties were studied by the voltammetry method. Influence of the lithium compounds on the immune cells of human blood were determined by measuring phagocytic activity of leucocytes and by the rate of blastic transformation of lymphocytes. Results: Relatively better antioxidant and immunotropic properties have been revealed for lithium ascorbate, compare to widely used drug-lithium carbonate. Lithium aspartate revealed antioxidant activity, as well. Conclusion: Studied lithium salts can be considered as prospective psychotropic antioxidant with immunomodulatory effects. The combination of these properties significantly extends the potential medical applications of lithium salts.

Язык оригиналаАнглийский
Страницы (с-по)107-113
Число страниц7
ЖурналPhysiology and Pharmacology
Том19
Номер выпуска2
СостояниеОпубликовано - 1 июн 2015

Отпечаток

Lithium
Antioxidants
Lithium Compounds
Salts
alcoholism
Lithium Carbonate
Cluster Headache
medicine
drug
Lymphocyte Activation
Bipolar Disorder
Aspartic Acid
Psychotic Disorders
Alcoholism
Blood Cells
Leukocytes
Salt
Cells
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Pharmacology
  • Physiology

Цитировать

Lithium-based antioxidants : Electrochemical properties and influence on immune cells. / Plotnikov, Evgenii; Korotkova, Elena; Voronova, Olesya Alexandrovna; Dorozhko, Elena; Bohan, Nikolay; Plotnikov, Sergey.

В: Physiology and Pharmacology, Том 19, № 2, 01.06.2015, стр. 107-113.

Результат исследований: Материалы для журналаСтатья

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AU - Voronova, Olesya Alexandrovna

AU - Dorozhko, Elena

AU - Bohan, Nikolay

AU - Plotnikov, Sergey

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