Janus glycosides of next generation: Synthesis of 4-(3-chloropropoxy)phenyl and 4-(3-azidopropoxy)phenyl glycosides

Elena V. Stepanova, Polina I. Abronina, Alexander I. Zinin, Alexander O. Chizhov, Leonid O. Kononov

Результат исследований: Материалы для журналаСтатья

1 цитирование (Scopus)

Выдержка

Efficient procedures for the preparative synthesis of per-O-acyl derivatives of 4-(3-chloropropoxy)phenyl (CPP) glycosides of a series of common mono- and disaccharides (D-glucose, D-galactose, D-mannose, L-rhamnose, D-arabinofuranose, D-glucosamine, lactose) are described. The CPP glycosides obtained were transformed in almost quantitative yields to the corresponding unprotected 4-(3-azidopropoxy)phenyl (APP) glycosides, which could become next-generation Janus glycosides with cleavable spacer aglycon, ready for conjugation or further transformation.

Язык оригиналаАнглийский
Страницы (с-по)95-104
Число страниц10
ЖурналCarbohydrate Research
DOI
СостояниеОпубликовано - 1 янв 2019

Отпечаток

Glycosides
Rhamnose
Monosaccharides
Disaccharides
Glucosamine
Lactose
Mannose
Galactose
Derivatives
Glucose

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Organic Chemistry

Цитировать

Janus glycosides of next generation : Synthesis of 4-(3-chloropropoxy)phenyl and 4-(3-azidopropoxy)phenyl glycosides. / Stepanova, Elena V.; Abronina, Polina I.; Zinin, Alexander I.; Chizhov, Alexander O.; Kononov, Leonid O.

В: Carbohydrate Research, 01.01.2019, стр. 95-104.

Результат исследований: Материалы для журналаСтатья

Stepanova, Elena V. ; Abronina, Polina I. ; Zinin, Alexander I. ; Chizhov, Alexander O. ; Kononov, Leonid O. / Janus glycosides of next generation : Synthesis of 4-(3-chloropropoxy)phenyl and 4-(3-azidopropoxy)phenyl glycosides. В: Carbohydrate Research. 2019 ; стр. 95-104.
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AU - Chizhov, Alexander O.

AU - Kononov, Leonid O.

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