In vitro assessment of hydroxyapatite coating on the surface of additive manufactured ti6al4v scaffolds

Ekaterina Chudinova, Maria Surmeneva, Andrey Koptioug, Irina Savintseva, Irina Selezneva, Per Skoglund, M. Syrtanov, Roman Surmenev

Результат исследований: Материалы для книги/типы отчетовМатериалы для конференции

1 Цитирования (Scopus)

Аннотация

Custom orthopedic and dental implants may be fabricated by additive manufacturing (AM), for example using electron beam melting technology. This study is focused on the modification of the surface of Ti6Al4V alloy coin-like scaffolds fabricated via AM technology (EBM®) by radio frequency (RF) magnetron sputter deposition of hydroxyapatite (HA) coating. The scaffolds with HA coating were characterized by Scanning Electron microscopy, X-ray diffraction. HA coating showed a nanocrystalline structure with the crystallites of an average size of 32±9 nm. The ability of the surface to support adhesion and the proliferation of human mesenchymal stem cells was studied using biological short-term tests in vitro. In according to in vitro assessment, thin HA coating stimulated the attachment and proliferation of cells. Human mesenchymal stem cells cultured on the HA-coated scaffold also formed mineralized nodules.

Язык оригиналаАнглийский
Название основной публикацииTHERMEC 2016
ИздательTrans Tech Publications Ltd
Страницы2444-2449
Число страниц6
Том879
ISBN (печатное издание)9783035711295
DOI
СостояниеОпубликовано - 2017
Событие9th International Conference on Processing and Manufacturing of Advanced Materials, THERMEC 2016 - Graz, Австрия
Продолжительность: 29 мая 20163 июн 2016

Серия публикаций

НазваниеMaterials Science Forum
Том879
ISSN (печатное издание)0255-5476

Конференция

Конференция9th International Conference on Processing and Manufacturing of Advanced Materials, THERMEC 2016
СтранаАвстрия
ГородGraz
Период29.5.163.6.16

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ASJC Scopus subject areas

  • Materials Science(all)
  • Condensed Matter Physics
  • Mechanics of Materials
  • Mechanical Engineering

Цитировать

Chudinova, E., Surmeneva, M., Koptioug, A., Savintseva, I., Selezneva, I., Skoglund, P., Syrtanov, M., & Surmenev, R. (2017). In vitro assessment of hydroxyapatite coating on the surface of additive manufactured ti6al4v scaffolds. В THERMEC 2016 (Том 879, стр. 2444-2449). (Materials Science Forum; Том 879). Trans Tech Publications Ltd. https://doi.org/10.4028/www.scientific.net/MSF.879.2444