Histological study of subcutaneous fat at NIR laser treatment of the rat skin in vivo

I. Yu Yanina, Yu I. Svenskaya, N. A. Navolokin, O. V. Matveeva, A. B. Bucharskaya, G. N. Maslyakova, D. A. Gorin, G. B. Sukhorukov, V. V. Tuchin

Результат исследований: Материалы для книги/типы отчетовМатериалы для конференции

Аннотация

The goal of this work is to quantify impact of in vivo photochemical treatment using indocyanine green (ICG) or encapsulated ICG and NIR laser irradiation through skin of rat with obesity by the follow up tissue sampling and histochemistry. After 1 hour elapsed since 1-min light exposure samples of rat skin with subcutaneous tissue of thickness of 1.5-2.5 mm were taken by surgery from rats within marked 4-zones of the skin site. For hematoxylin-eosin histological examination of excised tissue samples, fixation was carried out by 10%-formaldehyde solution. For ICG and encapsulated ICG subcutaneous injection and subsequent 1-min diode laser irradiation with power density of 8 W/cm2, different necrotic regions with lipolysis of subcutaneous fat were observed. The obtained data can be used for safe layer-by-layer laser treatment of obesity and cellulite.

Язык оригиналаАнглийский
Название основной публикацииMedical Laser Applications and Laser-Tissue Interactions VII
ИздательSPIE
Том9542
ISBN (электронное издание)9781628417074
DOI
СостояниеОпубликовано - 2015
Опубликовано для внешнего пользованияДа
СобытиеMedical Laser Applications and Laser Tissue Interactions VII - Munich, Германия
Продолжительность: 21 июн 201523 июн 2015

Конференция

КонференцияMedical Laser Applications and Laser Tissue Interactions VII
СтранаГермания
ГородMunich
Период21.6.1523.6.15

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

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