Flexible intramedullary nails for limb lengthening: a comprehensive comparative study of three nails types

E. N. Bolbasov, D. A. Popkov, N. A. Kononovich, E. N. Gorbach, I. A. Khlusov, A. S. Golovkin, K. S. Stankevich, V. P. Ignatov, V. M. Bouznik, Y. G. Anissimov, S. I. Tverdokhlebov, A. V. Popkov

Результат исследований: Материалы для журналаСтатья

Выдержка

This study aims to investigate the comparative study of calcium phosphate coatings for flexible intramedullary nails (FINs) used to lengthen long tubular bones. The presence of a calcium phosphate coating deposited by micro-arc oxidation (MAO) or a composite coating based on a co-polymer of vinylidene fluoride with tetrafluoroethylene (VDF-TeFE) and hydroxyapatite (HA) on the surface of the FIN significantly enhanced the regeneration of bone in the area of osteotomy during limb lengthening by combined osteosynthesis. The investigation of the physico-chemical properties of the FIN coated with calcium phosphate via MAO demonstrated that the improved bone tissue formation resulted from favourable conditions for adhesion, proliferation and differentiation of multipotent stem cells into osteoblasts on the coating surface. The composite coatings only stimulated the formation of bone tissue in vivo, primarily because of the piezoelectric properties of the VDF-TeFE co-polymer.

Язык оригиналаАнглийский
Число страниц1
ЖурналBiomedical materials (Bristol, England)
Том14
Номер выпуска2
DOI
СостояниеОпубликовано - 7 янв 2019

Отпечаток

Nails
Bone
Calcium phosphate
Phosphate coatings
Composite coatings
Coatings
Polymers
Tissue
Oxidation
Osteoblasts
Durapatite
Stem cells
Hydroxyapatite
Chemical properties
Adhesion
calcium phosphate
1,1-difluoroethylene
tetrafluoroethylene

ASJC Scopus subject areas

  • Bioengineering
  • Biomaterials
  • Biomedical Engineering

Цитировать

Flexible intramedullary nails for limb lengthening : a comprehensive comparative study of three nails types. / Bolbasov, E. N.; Popkov, D. A.; Kononovich, N. A.; Gorbach, E. N.; Khlusov, I. A.; Golovkin, A. S.; Stankevich, K. S.; Ignatov, V. P.; Bouznik, V. M.; Anissimov, Y. G.; Tverdokhlebov, S. I.; Popkov, A. V.

В: Biomedical materials (Bristol, England), Том 14, № 2, 07.01.2019.

Результат исследований: Материалы для журналаСтатья

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abstract = "This study aims to investigate the comparative study of calcium phosphate coatings for flexible intramedullary nails (FINs) used to lengthen long tubular bones. The presence of a calcium phosphate coating deposited by micro-arc oxidation (MAO) or a composite coating based on a co-polymer of vinylidene fluoride with tetrafluoroethylene (VDF-TeFE) and hydroxyapatite (HA) on the surface of the FIN significantly enhanced the regeneration of bone in the area of osteotomy during limb lengthening by combined osteosynthesis. The investigation of the physico-chemical properties of the FIN coated with calcium phosphate via MAO demonstrated that the improved bone tissue formation resulted from favourable conditions for adhesion, proliferation and differentiation of multipotent stem cells into osteoblasts on the coating surface. The composite coatings only stimulated the formation of bone tissue in vivo, primarily because of the piezoelectric properties of the VDF-TeFE co-polymer.",
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AU - Bolbasov, E. N.

AU - Popkov, D. A.

AU - Kononovich, N. A.

AU - Gorbach, E. N.

AU - Khlusov, I. A.

AU - Golovkin, A. S.

AU - Stankevich, K. S.

AU - Ignatov, V. P.

AU - Bouznik, V. M.

AU - Anissimov, Y. G.

AU - Tverdokhlebov, S. I.

AU - Popkov, A. V.

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