Аннотация
We have created novel HER2-overexpressing human ovarian adenocarcinoma cell line stably transfected with far-red fluorescent protein TurboFP635. Growth characteristics, adhesion capacity and morphology of the cells do not differ from that of parental cell line. The obtained cell line (SKOV-kat) was confirmed to have high level of expression of the tumor marker HER2 comparable to that of initial cell line SKOV-3. The SKOV-kat cell line is designed for further establishment of experimental fluorescent models of HER2-overexpressing human ovarian cancer that make it possible to optimize and reduce the cost of preclinical study of agents for treatment of this disease.
Язык оригинала | Английский |
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Страницы (с-по) | 410-412 |
Число страниц | 3 |
Журнал | Doklady Biochemistry and Biophysics |
Том | 465 |
Номер выпуска | 1 |
DOI | |
Состояние | Опубликовано - 1 ноя 2015 |
Опубликовано для внешнего пользования | Да |
ASJC Scopus subject areas
- Biophysics
- Chemistry(all)
- Medicine(all)
- Biochemistry