Fabrication and properties of L-arginine-doped PCL electrospun composite scaffolds

S. I. Goreninskii, E. N. Bolbasov, E. A. Sudarev, K. S. Stankevich, Y. G. Anissimov, A. S. Golovkin, A. I. Mishanin, A. N. Viknianshchuk, V. D. Filimonov, S. I. Tverdokhlebov

Результат исследований: Материалы для журналаСтатья

Выдержка

The article describes fabrication and properties of composite fibrous scaffolds obtained by electrospinning of the solution of poly(ε-caprolactone) and arginine in hexafluoro-2-propanol for the first time. The influence of arginine content on structure, mechanical, surface and biological properties of the scaffolds was investigated. It was found that arginine addition reduces diameter of the scaffold fibers and doesn't impair mechanical properties of the polymer. Porosity and water contact angle of the scaffold were independent from arginine content. The best adhesion and viability of multipotent mesenchymal stem cells was shown on scaffolds with arginine concentration from 0.5 to 1% wt.

Язык оригиналаАнглийский
Страницы (с-по)64-67
Число страниц4
ЖурналMaterials Letters
Том214
DOI
СостояниеОпубликовано - 1 мар 2018

Отпечаток

Arginine
Scaffolds
Fabrication
fabrication
composite materials
Composite materials
mechanical properties
stem cells
viability
surface properties
adhesion
porosity
Electrospinning
Propanol
Stem cells
fibers
polymers
Contact angle
Polymers
Adhesion

ASJC Scopus subject areas

  • Materials Science(all)
  • Condensed Matter Physics
  • Mechanics of Materials
  • Mechanical Engineering

Цитировать

Fabrication and properties of L-arginine-doped PCL electrospun composite scaffolds. / Goreninskii, S. I.; Bolbasov, E. N.; Sudarev, E. A.; Stankevich, K. S.; Anissimov, Y. G.; Golovkin, A. S.; Mishanin, A. I.; Viknianshchuk, A. N.; Filimonov, V. D.; Tverdokhlebov, S. I.

В: Materials Letters, Том 214, 01.03.2018, стр. 64-67.

Результат исследований: Материалы для журналаСтатья

Goreninskii, S. I. ; Bolbasov, E. N. ; Sudarev, E. A. ; Stankevich, K. S. ; Anissimov, Y. G. ; Golovkin, A. S. ; Mishanin, A. I. ; Viknianshchuk, A. N. ; Filimonov, V. D. ; Tverdokhlebov, S. I. / Fabrication and properties of L-arginine-doped PCL electrospun composite scaffolds. В: Materials Letters. 2018 ; Том 214. стр. 64-67.
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abstract = "The article describes fabrication and properties of composite fibrous scaffolds obtained by electrospinning of the solution of poly(ε-caprolactone) and arginine in hexafluoro-2-propanol for the first time. The influence of arginine content on structure, mechanical, surface and biological properties of the scaffolds was investigated. It was found that arginine addition reduces diameter of the scaffold fibers and doesn't impair mechanical properties of the polymer. Porosity and water contact angle of the scaffold were independent from arginine content. The best adhesion and viability of multipotent mesenchymal stem cells was shown on scaffolds with arginine concentration from 0.5 to 1{\%} wt.",
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author = "Goreninskii, {S. I.} and Bolbasov, {E. N.} and Sudarev, {E. A.} and Stankevich, {K. S.} and Anissimov, {Y. G.} and Golovkin, {A. S.} and Mishanin, {A. I.} and Viknianshchuk, {A. N.} and Filimonov, {V. D.} and Tverdokhlebov, {S. I.}",
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AU - Goreninskii, S. I.

AU - Bolbasov, E. N.

AU - Sudarev, E. A.

AU - Stankevich, K. S.

AU - Anissimov, Y. G.

AU - Golovkin, A. S.

AU - Mishanin, A. I.

AU - Viknianshchuk, A. N.

AU - Filimonov, V. D.

AU - Tverdokhlebov, S. I.

PY - 2018/3/1

Y1 - 2018/3/1

N2 - The article describes fabrication and properties of composite fibrous scaffolds obtained by electrospinning of the solution of poly(ε-caprolactone) and arginine in hexafluoro-2-propanol for the first time. The influence of arginine content on structure, mechanical, surface and biological properties of the scaffolds was investigated. It was found that arginine addition reduces diameter of the scaffold fibers and doesn't impair mechanical properties of the polymer. Porosity and water contact angle of the scaffold were independent from arginine content. The best adhesion and viability of multipotent mesenchymal stem cells was shown on scaffolds with arginine concentration from 0.5 to 1% wt.

AB - The article describes fabrication and properties of composite fibrous scaffolds obtained by electrospinning of the solution of poly(ε-caprolactone) and arginine in hexafluoro-2-propanol for the first time. The influence of arginine content on structure, mechanical, surface and biological properties of the scaffolds was investigated. It was found that arginine addition reduces diameter of the scaffold fibers and doesn't impair mechanical properties of the polymer. Porosity and water contact angle of the scaffold were independent from arginine content. The best adhesion and viability of multipotent mesenchymal stem cells was shown on scaffolds with arginine concentration from 0.5 to 1% wt.

KW - Biomaterials

KW - Electrospun scaffolds

KW - L-arginine

KW - Polycaprolactone

KW - Polymeric composites

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