Effect of nitro derivatives on electromechanical coupling in ureteral smooth muscle cells

Аннотация

Double sucrose gap experiments revealed differences in the effect of nitroglycerin and sodium nitroprusside on action potential and contraction of ureteral smooth muscle cells. Unlike sodium nitroprusside, nitroglycerin inhibited voltage-dependent Ca²⁺ membrane permeability. It was concluded that cGMP-independent mechanisms of the effects of nitro derivative reflect the peculiarities of excitation-contraction coupling in smooth muscles.

Язык оригинала	Английский
Страницы (с-по)	455-457
Число страниц	3
Журнал	Bulletin of Experimental Biology and Medicine
Том	129
Номер выпуска	5
Состояние	Опубликовано - 2000
Опубликовано для внешнего пользования	Да

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)

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Цитировать

Kovalev, I. V., Popov, A. G., Panov, A. A., Borodin, Y. L., Kapilevich, L. V., Anfinogenova, Y. J., Baskakov, M. B., & Medvedev, M. A. (2000). Effect of nitro derivatives on electromechanical coupling in ureteral smooth muscle cells. Bulletin of Experimental Biology and Medicine, 129(5), 455-457.

Effect of nitro derivatives on electromechanical coupling in ureteral smooth muscle cells. / Kovalev, I. V.; Popov, A. G.; Panov, A. A.; Borodin, Yu L.; Kapilevich, L. V.; Anfinogenova, Yana Jonovna; Baskakov, M. B.; Medvedev, M. A.

В: Bulletin of Experimental Biology and Medicine, Том 129, № 5, 2000, стр. 455-457.

Результат исследований: Материалы для журнала › Статья

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author = "Kovalev, {I. V.} and Popov, {A. G.} and Panov, {A. A.} and Borodin, {Yu L.} and Kapilevich, {L. V.} and Anfinogenova, {Yana Jonovna} and Baskakov, {M. B.} and Medvedev, {M. A.}",

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AU - Kovalev, I. V.

AU - Popov, A. G.

AU - Panov, A. A.

AU - Borodin, Yu L.

AU - Kapilevich, L. V.

AU - Anfinogenova, Yana Jonovna

AU - Baskakov, M. B.

AU - Medvedev, M. A.

PY - 2000

Y1 - 2000

N2 - Double sucrose gap experiments revealed differences in the effect of nitroglycerin and sodium nitroprusside on action potential and contraction of ureteral smooth muscle cells. Unlike sodium nitroprusside, nitroglycerin inhibited voltage-dependent Ca2+ membrane permeability. It was concluded that cGMP-independent mechanisms of the effects of nitro derivative reflect the peculiarities of excitation-contraction coupling in smooth muscles.

AB - Double sucrose gap experiments revealed differences in the effect of nitroglycerin and sodium nitroprusside on action potential and contraction of ureteral smooth muscle cells. Unlike sodium nitroprusside, nitroglycerin inhibited voltage-dependent Ca2+ membrane permeability. It was concluded that cGMP-independent mechanisms of the effects of nitro derivative reflect the peculiarities of excitation-contraction coupling in smooth muscles.

KW - Ionic membrane permeability

KW - Nitro derivatives

KW - Smooth muscle cells

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