@inproceedings{b5134606f1174959b8be1b0daee785e2,
title = "Development and study of 99mTc-1-Thio-D-glucose for visualization of malignant tumors",
abstract = "The preclinical studies of 99mTc-1-Thio-D-glucose, a new tumor-seeking agent based on technetium-99m-labeled glucose derivative, were conducted, and the feasibility of using this radiopharmaceutical for tumor visualization was studied. The preclinical studies were carried out strictly in accordance with the local legislation and were regulated by the generally accepted research standards. 99mTc-1-Thio-D-glucose was found to have optimal pharmacokinetic and physico-chemical properties for diagnostic imaging and was proved to belong to the low-toxic substances. The potential utility of 99mTc-1-thio-D-glucose for tumor imaging was studied in vitro and in vivo models. The present study demonstrated that 99mTc-1-Thio-D-glucose is a prospective radiopharmaceutical for cancer visualization.",
author = "R. Zeltchan and A. Medvedeva and I. Sinilkin and O. Bragina and V. Chernov and E. Stasyuk and A. Rogov and E. Il'Ina and V. Skuridin",
year = "2017",
month = sep,
day = "28",
doi = "10.1063/1.5001662",
language = "English",
series = "AIP Conference Proceedings",
publisher = "American Institute of Physics Inc.",
editor = "Gutmanas, {Elazar Y.} and Naimark, {Oleg B.} and Sharkeev, {Yurii P.}",
booktitle = "Physics of Cancer",
note = "International Conference on Physics of Cancer: Interdisciplinary Problems and Clinical Applications, PC IPCA 2017 ; Conference date: 23-05-2017 Through 26-05-2017",
}