Cytotoxicity of Titanium Oxynitride Obtained by Reactive Magnetron Sputtered on Endothelial Cell Line EA.hy 926

Maria Surovtseva, Olga Poveshchenko, Irina Kim, Vladimir Pichugin, Irina Zhuravleva

Результат исследований: Материалы для книги/типы отчетовМатериалы для конференции

Аннотация

One of the current areas of medical materials science is the formation of ultrathin coatings on the surface of implants. Among the many types of coating used in vascular surgery, binary and ternary titanium compounds have good prospects due to their high bio- and hemocompatibility. The properties of the coating based on films of nitrogen-containing titanium oxide (titanium oxynitride), applied by reactive magnetron sputtering (RMS), was studied. While problems of establishing and maintaining the necessary spraying mode is relevant for the RMS technique. The cytotoxicity of the titanium oxy nitride compounds obtained under various modes of functioning of RMS on endothelial cells line EA.hy 926 was the aim of this report. It was showed that the levels of nitric oxide (NO) production by EA.hy 926 cell line on Day 1 and Day 5 growth under the different samples of nitinol treated with different RMS modes was comparable to control. It was no obtained cytotoxic effect of the nitrogen-containing coatings of titanium oxide obtained by various modes of RMS on EA.hy 926 cell line. While was observed reduced levels of NO production by EA.hy 926 cell line on Day 3.

Язык оригиналаАнглийский
Название основной публикацииProceedings - 2020 Cognitive Sciences, Genomics and Bioinformatics, CSGB 2020
ИздательInstitute of Electrical and Electronics Engineers Inc.
Страницы286-289
Число страниц4
ISBN (электронное издание)9781728195971
DOI
СостояниеОпубликовано - июл 2020
Событие2020 Cognitive Sciences, Genomics and Bioinformatics, CSGB 2020 - Novosibirsk, Российская Федерация
Продолжительность: 6 июл 202010 июл 2020

Серия публикаций

НазваниеProceedings - 2020 Cognitive Sciences, Genomics and Bioinformatics, CSGB 2020

Конференция

Конференция2020 Cognitive Sciences, Genomics and Bioinformatics, CSGB 2020
СтранаРоссийская Федерация
ГородNovosibirsk
Период6.7.2010.7.20

ASJC Scopus subject areas

  • Information Systems
  • Decision Sciences (miscellaneous)
  • Cognitive Neuroscience
  • Health Informatics
  • Genetics
  • Artificial Intelligence
  • Computer Science Applications

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