Conformational stability of leukocyte lactate dehydrogenase in healthy men of different age

O. Yu Fedorenko, N. A. Bokhan, S. A. Ivanova

Результат исследований: Материалы для журналаСтатья

1 Цитирования (Scopus)

Аннотация

Comparative analysis of cytosolic fraction distribution and conformational stability in lactate dehydrogenase (LDH) isozymes in healthy men of different age revealed significant differences indicating age-related characteristics of the enzyme. Activity of cytosolic fraction of LDH-1 and conformational stability of LDH-2 and LDH-3 in 40-year-old men were higher than in 20-year-olds. These data suggest age-related determination of conformational stability of individual LDH isozymes and functional heterogeneity of the enzyme within each isoform.

Язык оригиналаАнглийский
Страницы (с-по)44-46
Число страниц3
ЖурналBulletin of Experimental Biology and Medicine
Том154
Номер выпуска1
DOI
СостояниеОпубликовано - ноя 2012

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Fingerprint Подробные сведения о темах исследования «Conformational stability of leukocyte lactate dehydrogenase in healthy men of different age». Вместе они формируют уникальный семантический отпечаток (fingerprint).

  • Цитировать