Conformational stability of leukocyte lactate dehydrogenase in healthy men of different age

O. Yu Fedorenko, N. A. Bokhan, S. A. Ivanova

Результат исследования: Материалы для журналаСтатья

1 Цитирования (Scopus)

Аннотация

Comparative analysis of cytosolic fraction distribution and conformational stability in lactate dehydrogenase (LDH) isozymes in healthy men of different age revealed significant differences indicating age-related characteristics of the enzyme. Activity of cytosolic fraction of LDH-1 and conformational stability of LDH-2 and LDH-3 in 40-year-old men were higher than in 20-year-olds. These data suggest age-related determination of conformational stability of individual LDH isozymes and functional heterogeneity of the enzyme within each isoform.

Язык оригиналаАнглийский
Страницы (с... по...)44-46
Количество страниц3
ЖурналBulletin of Experimental Biology and Medicine
Том154
Номер выпуска1
DOI
Статус публикацииОпубликовано - ноя 2012

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ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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