Comparative scintigraphic study of 99mTc ciprofloxacin pharmacokinetics after intravenous and lymphotropic administration in experimental pulmonary suppuration

Yu B. Lishmanov, Svetlana Ivanovna Sazonova, E. G. Sokolovich, V. I. Chernov

Результат исследований: Материалы для журналаСтатьярецензирование

1 Цитирования (Scopus)

Аннотация

Intravenously injected 99mTc ciprofloxacin is rapidly accumulated and washed from the septic focus. Lymphotropic injections provide targeted and long-lasting effect of the antibiotic. After injection into the interspinous ligament the drug slowly enters the inflammation area (by-passing the urinary organs and liver), where it is maximally accumulated only after 24 h, which allows to reduce the number of injections and the total dose of the antibiotic.

Язык оригиналаАнглийский
Страницы (с-по)94-97
Число страниц4
ЖурналBulletin of Experimental Biology and Medicine
Том139
Номер выпуска1
DOI
СостояниеОпубликовано - янв 2005

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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