Выдержка
Metalloenzymes that carry a pterin-based molybdenum cofactor in their center catalyze numerous reactions in the human body and play a crucial role in its metabolism. Specifically, these enzymes promote redox reactions and oxygen transport in the body. Their absence may cause many problems leading to disability or even death in early childhood. Therefore, model compounds need to be synthesized and analyzed to investigate the reactivity, redox potential, and geometry of these cofactors. This study focused on electrode processes and determined the redox potentials of the new bis-(4-mercapto-5-(p-tolyl)-3H-1,2-dithiole-3-thione)-dioxomolybdenum complex by cyclic voltammetry. The 4-mercapto-5-(p-tolyl)-3H-1,2-dithiole-3-thione ligand underwent irreversible oxidation and reduction at thiol and thione functional groups. The new dioxomolybdenum complex showed a quasi-reversible two-stage electrode process.
| Язык оригинала | Английский |
|---|---|
| Страницы (с-по) | 2369-2379 |
| Число страниц | 11 |
| Журнал | Analytical Letters |
| Том | 48 |
| Номер выпуска | 15 |
| DOI | |
| Состояние | Опубликовано - 13 окт 2015 |
Отпечаток
ASJC Scopus subject areas
- Analytical Chemistry
- Biochemistry
- Clinical Biochemistry
- Biochemistry, medical
- Electrochemistry
- Spectroscopy
Цитировать
Characterization of a Novel Dioxomolybdenum Complex by Cyclic Voltammetry. / Knittl, Esther Theresa; Rusakov, D. A.; Korotkova, E. I.; Dorozhko, E. V.; Voronova, Olesya Alexandrovna; Plotnikov, E. V.; Topaloglu-Sozuer, Isil; Linert, Wolfgang.
В: Analytical Letters, Том 48, № 15, 13.10.2015, стр. 2369-2379.Результат исследований: Материалы для журнала › Статья
}
TY - JOUR
T1 - Characterization of a Novel Dioxomolybdenum Complex by Cyclic Voltammetry
AU - Knittl, Esther Theresa
AU - Rusakov, D. A.
AU - Korotkova, E. I.
AU - Dorozhko, E. V.
AU - Voronova, Olesya Alexandrovna
AU - Plotnikov, E. V.
AU - Topaloglu-Sozuer, Isil
AU - Linert, Wolfgang
PY - 2015/10/13
Y1 - 2015/10/13
N2 - Metalloenzymes that carry a pterin-based molybdenum cofactor in their center catalyze numerous reactions in the human body and play a crucial role in its metabolism. Specifically, these enzymes promote redox reactions and oxygen transport in the body. Their absence may cause many problems leading to disability or even death in early childhood. Therefore, model compounds need to be synthesized and analyzed to investigate the reactivity, redox potential, and geometry of these cofactors. This study focused on electrode processes and determined the redox potentials of the new bis-(4-mercapto-5-(p-tolyl)-3H-1,2-dithiole-3-thione)-dioxomolybdenum complex by cyclic voltammetry. The 4-mercapto-5-(p-tolyl)-3H-1,2-dithiole-3-thione ligand underwent irreversible oxidation and reduction at thiol and thione functional groups. The new dioxomolybdenum complex showed a quasi-reversible two-stage electrode process.
AB - Metalloenzymes that carry a pterin-based molybdenum cofactor in their center catalyze numerous reactions in the human body and play a crucial role in its metabolism. Specifically, these enzymes promote redox reactions and oxygen transport in the body. Their absence may cause many problems leading to disability or even death in early childhood. Therefore, model compounds need to be synthesized and analyzed to investigate the reactivity, redox potential, and geometry of these cofactors. This study focused on electrode processes and determined the redox potentials of the new bis-(4-mercapto-5-(p-tolyl)-3H-1,2-dithiole-3-thione)-dioxomolybdenum complex by cyclic voltammetry. The 4-mercapto-5-(p-tolyl)-3H-1,2-dithiole-3-thione ligand underwent irreversible oxidation and reduction at thiol and thione functional groups. The new dioxomolybdenum complex showed a quasi-reversible two-stage electrode process.
KW - Cyclic voltammetry
KW - Dioxomolybdenum complex
KW - Glassy carbon electrode
KW - Redox properties
UR - http://www.scopus.com/inward/record.url?scp=84938412328&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84938412328&partnerID=8YFLogxK
U2 - 10.1080/00032719.2015.1038555
DO - 10.1080/00032719.2015.1038555
M3 - Article
AN - SCOPUS:84938412328
VL - 48
SP - 2369
EP - 2379
JO - Analytical Letters
JF - Analytical Letters
SN - 0003-2719
IS - 15
ER -