Changes in the plasma levels of myokines after different physical exercises in athletes and untrained individuals

L. V. Kapilevich, A. N. Zakharova, A. V. Kabachkova, T. A. Kironenko, E. Yu Dyakova, S. N. Orlov

Результат исследований: Материалы для журналаСтатья

Выдержка

The influence of dynamic and static load on the plasma level of myokines in strength-and endurance-trained athletes and untrained subjects has been studied. The range of myokines has been found to depend on the type of loads and the level of fitness. Dynamic and static exercises have different effects on the level of myokines in athletes and untrained subjects. The dynamic load increases the level of IL-6 and IL-8 in the plasma of athletes, while the static load increases the concentration of IL-15 and LIF. At the same time, no increase in the level of IL-8 after cyclic loading or in IL-15 after a static load has been observed in the control group. These differences may be based on a number of mechanisms. The cellular composition of skeletal muscles and the phenotypic features of muscle fibers, changing as a result of regular exercise, can modify the processes of myokine production. However, the processes of transcription in muscle fibers are much more important; the most important ones are HIF-1α, [Ca2+]i and [Na+]i/[K+]i-dependent intracellular signaling pathways. The modification of these mechanisms caused by different physical loads and intensity is of great interest since it is a promising way to influence the metabolic processes at the cellular and systemic levels, which is very helpful in both improving athletic performance and correcting metabolic disorders in a number of socially significant diseases.

Язык оригиналаАнглийский
Страницы (с-по)312-319
Число страниц8
ЖурналHuman Physiology
Том43
Номер выпуска3
DOI
СостояниеОпубликовано - 1 мая 2017

Отпечаток

Athletes
Interleukin-15
Exercise
Interleukin-8
Athletic Performance
Muscles
Interleukin-6
Skeletal Muscle
Control Groups

ASJC Scopus subject areas

  • Physiology
  • Physiology (medical)

Цитировать

Changes in the plasma levels of myokines after different physical exercises in athletes and untrained individuals. / Kapilevich, L. V.; Zakharova, A. N.; Kabachkova, A. V.; Kironenko, T. A.; Dyakova, E. Yu; Orlov, S. N.

В: Human Physiology, Том 43, № 3, 01.05.2017, стр. 312-319.

Результат исследований: Материалы для журналаСтатья

Kapilevich, L. V. ; Zakharova, A. N. ; Kabachkova, A. V. ; Kironenko, T. A. ; Dyakova, E. Yu ; Orlov, S. N. / Changes in the plasma levels of myokines after different physical exercises in athletes and untrained individuals. В: Human Physiology. 2017 ; Том 43, № 3. стр. 312-319.
@article{e7f179fd95b54244a08bb4fc57346dbe,
title = "Changes in the plasma levels of myokines after different physical exercises in athletes and untrained individuals",
abstract = "The influence of dynamic and static load on the plasma level of myokines in strength-and endurance-trained athletes and untrained subjects has been studied. The range of myokines has been found to depend on the type of loads and the level of fitness. Dynamic and static exercises have different effects on the level of myokines in athletes and untrained subjects. The dynamic load increases the level of IL-6 and IL-8 in the plasma of athletes, while the static load increases the concentration of IL-15 and LIF. At the same time, no increase in the level of IL-8 after cyclic loading or in IL-15 after a static load has been observed in the control group. These differences may be based on a number of mechanisms. The cellular composition of skeletal muscles and the phenotypic features of muscle fibers, changing as a result of regular exercise, can modify the processes of myokine production. However, the processes of transcription in muscle fibers are much more important; the most important ones are HIF-1α, [Ca2+]i and [Na+]i/[K+]i-dependent intracellular signaling pathways. The modification of these mechanisms caused by different physical loads and intensity is of great interest since it is a promising way to influence the metabolic processes at the cellular and systemic levels, which is very helpful in both improving athletic performance and correcting metabolic disorders in a number of socially significant diseases.",
keywords = "athletes, dynamic and static exercise, inhibitory factor, interleukins, leukemia, myokines",
author = "Kapilevich, {L. V.} and Zakharova, {A. N.} and Kabachkova, {A. V.} and Kironenko, {T. A.} and Dyakova, {E. Yu} and Orlov, {S. N.}",
year = "2017",
month = "5",
day = "1",
doi = "10.1134/S0362119717030070",
language = "English",
volume = "43",
pages = "312--319",
journal = "Human Physiology",
issn = "0362-1197",
publisher = "Maik Nauka-Interperiodica Publishing",
number = "3",

}

TY - JOUR

T1 - Changes in the plasma levels of myokines after different physical exercises in athletes and untrained individuals

AU - Kapilevich, L. V.

AU - Zakharova, A. N.

AU - Kabachkova, A. V.

AU - Kironenko, T. A.

AU - Dyakova, E. Yu

AU - Orlov, S. N.

PY - 2017/5/1

Y1 - 2017/5/1

N2 - The influence of dynamic and static load on the plasma level of myokines in strength-and endurance-trained athletes and untrained subjects has been studied. The range of myokines has been found to depend on the type of loads and the level of fitness. Dynamic and static exercises have different effects on the level of myokines in athletes and untrained subjects. The dynamic load increases the level of IL-6 and IL-8 in the plasma of athletes, while the static load increases the concentration of IL-15 and LIF. At the same time, no increase in the level of IL-8 after cyclic loading or in IL-15 after a static load has been observed in the control group. These differences may be based on a number of mechanisms. The cellular composition of skeletal muscles and the phenotypic features of muscle fibers, changing as a result of regular exercise, can modify the processes of myokine production. However, the processes of transcription in muscle fibers are much more important; the most important ones are HIF-1α, [Ca2+]i and [Na+]i/[K+]i-dependent intracellular signaling pathways. The modification of these mechanisms caused by different physical loads and intensity is of great interest since it is a promising way to influence the metabolic processes at the cellular and systemic levels, which is very helpful in both improving athletic performance and correcting metabolic disorders in a number of socially significant diseases.

AB - The influence of dynamic and static load on the plasma level of myokines in strength-and endurance-trained athletes and untrained subjects has been studied. The range of myokines has been found to depend on the type of loads and the level of fitness. Dynamic and static exercises have different effects on the level of myokines in athletes and untrained subjects. The dynamic load increases the level of IL-6 and IL-8 in the plasma of athletes, while the static load increases the concentration of IL-15 and LIF. At the same time, no increase in the level of IL-8 after cyclic loading or in IL-15 after a static load has been observed in the control group. These differences may be based on a number of mechanisms. The cellular composition of skeletal muscles and the phenotypic features of muscle fibers, changing as a result of regular exercise, can modify the processes of myokine production. However, the processes of transcription in muscle fibers are much more important; the most important ones are HIF-1α, [Ca2+]i and [Na+]i/[K+]i-dependent intracellular signaling pathways. The modification of these mechanisms caused by different physical loads and intensity is of great interest since it is a promising way to influence the metabolic processes at the cellular and systemic levels, which is very helpful in both improving athletic performance and correcting metabolic disorders in a number of socially significant diseases.

KW - athletes

KW - dynamic and static exercise

KW - inhibitory factor

KW - interleukins

KW - leukemia

KW - myokines

UR - http://www.scopus.com/inward/record.url?scp=85021306664&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85021306664&partnerID=8YFLogxK

U2 - 10.1134/S0362119717030070

DO - 10.1134/S0362119717030070

M3 - Article

AN - SCOPUS:85021306664

VL - 43

SP - 312

EP - 319

JO - Human Physiology

JF - Human Physiology

SN - 0362-1197

IS - 3

ER -