Application of a 2D Molybdenum Telluride in SERS Detection of Biorelevant Molecules

James P. Fraser, Pavel Postnikov, Elena Miliutina, Zdenka Kolska, Rashid Valiev, Vaclav Švorčík, Oleksiy Lyutakov, Alexey Y. Ganin, Olga Guselnikova

Результат исследований: Материалы для журналаСтатьярецензирование

3 Цитирования (Scopus)

Аннотация

Two-dimensional (2D) transition-metal dichalcogenides have become promising candidates for surface-enhanced Raman spectroscopy (SERS), but currently very few examples of detection of relevant molecules are available. Herein, we show the detection of the lipophilic disease marker β-sitosterol on few-layered MoTe2 films. The chemical vapor deposition (CVD)-grown films are capable of nanomolar detection, exceeding the performance of alternative noble-metal surfaces. We confirm that the enhancement occurs through the chemical enhancement (CE) mechanism via formation of a surface-analyte complex, which leads to an enhancement factor of ≈104, as confirmed by Fourier transform infrared (FTIR), UV-vis, and cyclic voltammetry (CV) analyses and density functional theory (DFT) calculations. Low values of signal deviation over a seven-layered MoTe2 film confirms the homogeneity and reproducibility of the results in comparison to noble-metal substrate analogues. Furthermore, β-sitosterol detection within cell culture media, a minimal loss of signal over 50 days, and the opportunity for sensor regeneration suggest that MoTe2 can become a promising new SERS platform for biosensing.

Язык оригиналаАнглийский
Страницы (с-по)47774-47783
Число страниц10
ЖурналACS applied materials & interfaces
Том12
Номер выпуска42
DOI
СостояниеОпубликовано - 21 окт 2020

ASJC Scopus subject areas

  • Materials Science(all)

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