Antiviral activity of Bacillus intermedius RNAase in guinea-pigs and rabbits infected with outdoor rabies virus

S. V. Gribencha, L. A. Potseluyeva, I. F. Barinsky, S. M. Deyev, T. G. Balandin, I. B. Leshchinskaya

Результат исследований: Материалы для журналаСтатья

9 Цитирования (Scopus)

Аннотация

Single injection of Bacillus intermedius RNAase in a dose of 5 mg/kg could protect 40 and 50-70% of the outdoor rabies virus-preinfected guinea-pigs and rabbits, respectively. In the control group there were 100 and 75-100% deaths of the RNAase-untreated guinea-pigs and rabbits, respectively. Animal protection was observed only when RNAase was injected into the site of viral administration. The Intramuscular injection of RNAase, other than the site of viral administration failed to protect the infected animals, the efficacy (75%) of RNAase Injected into the rabbits was similar 1 and 24 hours after animal infection.

Язык оригиналаАнглийский
Страницы (с-по)41-43
Число страниц3
ЖурналVoprosy Virusologii
Том51
Номер выпуска5
СостояниеОпубликовано - 2006

ASJC Scopus subject areas

  • Virology

Fingerprint Подробные сведения о темах исследования «Antiviral activity of Bacillus intermedius RNAase in guinea-pigs and rabbits infected with outdoor rabies virus». Вместе они формируют уникальный семантический отпечаток (fingerprint).

  • Цитировать

    Gribencha, S. V., Potseluyeva, L. A., Barinsky, I. F., Deyev, S. M., Balandin, T. G., & Leshchinskaya, I. B. (2006). Antiviral activity of Bacillus intermedius RNAase in guinea-pigs and rabbits infected with outdoor rabies virus. Voprosy Virusologii, 51(5), 41-43.