Adsorption of 99m Tc under static and dynamic conditions on aluminum oxides subjected to various acid treatments at pH from 7.29 to 1.26 (until the reaction of the oxide with the acid fully ceased) was studied. In batch experiments, the maximal adsorption of 99m Tc, more than 30% of the radionuclide activity, is attained with the oxide that absorbed 2 × 10-4 mol g-1 acid. The "rate" of linear migration of 99m Tc in a chromatographic column in the course of elution with a 0.9% NaCl solution under the conditions of limiting saturation of the oxide with the acid is 0.49-0.52 cm ml-1. It is concluded that the observed deceleration of the 99m Tc elution from the generator column is due to its "braking" by active sites of the oxide. Upon reduction of 99m Tc with bivalent tin, its adsorption increases to 93.53%. The results obtained are of interest for the development of procedures for depositing 99m Tc onto the surface of nanosized colloidal particles of aluminum oxide for their subsequent use in medical diagnostics.
ASJC Scopus subject areas
- Physical and Theoretical Chemistry