TY - JOUR
T1 - A practical access to highly enantiomerically pure flavanones by catalytic asymmetric transfer hydrogenation
AU - Lemke, Marie Kristin
AU - Schwab, Pia
AU - Fischer, Petra
AU - Tischer, Sandra
AU - Witt, Morris
AU - Noehringer, Laurence
AU - Rogachev, Victor
AU - Jäger, Anne
AU - Kataeva, Olga
AU - Fröhlich, Roland
AU - Metz, Peter
PY - 2013/10/25
Y1 - 2013/10/25
N2 - A surprisingly selective, non-enzymatic kinetic resolution of readily available, racemic β-chiral ketones enabled the title process, which was applied to a rapid synthesis of several bioactive flavanones in virtually enantiopure form (see scheme; MOM=methoxymethyl, Ts=p-toluenesulfonyl).
AB - A surprisingly selective, non-enzymatic kinetic resolution of readily available, racemic β-chiral ketones enabled the title process, which was applied to a rapid synthesis of several bioactive flavanones in virtually enantiopure form (see scheme; MOM=methoxymethyl, Ts=p-toluenesulfonyl).
KW - asymmetric catalysis
KW - flavonoids
KW - glabrol
KW - kinetic resolution
KW - natural products
UR - http://www.scopus.com/inward/record.url?scp=84885983039&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84885983039&partnerID=8YFLogxK
U2 - 10.1002/anie.201306500
DO - 10.1002/anie.201306500
M3 - Article
C2 - 24027174
AN - SCOPUS:84885983039
VL - 52
SP - 11651
EP - 11655
JO - Angewandte Chemie - International Edition
JF - Angewandte Chemie - International Edition
SN - 1433-7851
IS - 44
ER -