A New, Simple, and General Synthesis of N -Oxides of Iodopyridines and Iodoquinolines via the Diazotization–Iodination of Heterocyclic Amino N -Oxides in the Presence of p -Toluenesulfonic Acid in Water

Результат исследования: Материалы для журналаСтатья

Аннотация

The diazotization of a series of N -oxides of aminopyridines and aminoquinolines under the action of sodium nitrite in the presence of KI and p -TsOH in water at room temperature leads to the formation of the corresponding N -oxides of iodopyridines and iodoquinolines in high yields. The method has a general character and can be used for the preparation of 3-, 2-, and 4- N -oxides of iodopyridines.

Язык оригиналаАнглийский
Страницы (с... по...)1368-1372
Количество страниц5
ЖурналSynthesis (Germany)
Том50
Номер выпуска6
DOI
Статус публикацииПринято/в печати - 13 дек 2017

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ASJC Scopus subject areas

  • Catalysis
  • Organic Chemistry

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