A comprehensive study of interactions between lectins and glycoproteins for the development of effective theranostic nanoagents

V. O. Shipunova, M. P. Nikitin, I. V. Zelepukin, P. I. Nikitin, S. M. Deyev, R. V. Petrov

Результат исследований: Материалы для журналаСтатья

5 Цитирования (Scopus)

Выдержка

A comprehensive study of the interactions between lectins and glycoproteins possessing different glycosylation profiles in the composition of nanoparticles was carried out in order to find specifically interacting protein pairs for the creation of novel classes of multifunctional nanoagets that based on protein-assisted selfassembly. We obtained information about specific interactions of certain lectins with selected glycoproteins as well as about the ability of certain monosaccharides to competitively inhibit binding of glycoproteins with lectins. These protein-mediated interactions may be involved in the formulation of self-assembled nanoparticles for therapy and diagnostics of various diseases.

Язык оригиналаАнглийский
Страницы (с-по)315-318
Число страниц4
ЖурналDoklady Biochemistry and Biophysics
Том464
Номер выпуска1
DOI
СостояниеОпубликовано - 1 сен 2015
Опубликовано для внешнего пользованияДа

Отпечаток

Lectins
Glycoproteins
Nanoparticles
Glycosylation
Proteins
Monosaccharides
Chemical analysis
Theranostic Nanomedicine
Therapeutics

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Chemistry(all)

Цитировать

A comprehensive study of interactions between lectins and glycoproteins for the development of effective theranostic nanoagents. / Shipunova, V. O.; Nikitin, M. P.; Zelepukin, I. V.; Nikitin, P. I.; Deyev, S. M.; Petrov, R. V.

В: Doklady Biochemistry and Biophysics, Том 464, № 1, 01.09.2015, стр. 315-318.

Результат исследований: Материалы для журналаСтатья

Shipunova, V. O. ; Nikitin, M. P. ; Zelepukin, I. V. ; Nikitin, P. I. ; Deyev, S. M. ; Petrov, R. V. / A comprehensive study of interactions between lectins and glycoproteins for the development of effective theranostic nanoagents. В: Doklady Biochemistry and Biophysics. 2015 ; Том 464, № 1. стр. 315-318.
@article{33eae9ad334d478b9a283e99599f3c1c,
title = "A comprehensive study of interactions between lectins and glycoproteins for the development of effective theranostic nanoagents",
abstract = "A comprehensive study of the interactions between lectins and glycoproteins possessing different glycosylation profiles in the composition of nanoparticles was carried out in order to find specifically interacting protein pairs for the creation of novel classes of multifunctional nanoagets that based on protein-assisted selfassembly. We obtained information about specific interactions of certain lectins with selected glycoproteins as well as about the ability of certain monosaccharides to competitively inhibit binding of glycoproteins with lectins. These protein-mediated interactions may be involved in the formulation of self-assembled nanoparticles for therapy and diagnostics of various diseases.",
author = "Shipunova, {V. O.} and Nikitin, {M. P.} and Zelepukin, {I. V.} and Nikitin, {P. I.} and Deyev, {S. M.} and Petrov, {R. V.}",
year = "2015",
month = "9",
day = "1",
doi = "10.1134/S1607672915050117",
language = "English",
volume = "464",
pages = "315--318",
journal = "Doklady Biochemistry and Biophysics",
issn = "1607-6729",
publisher = "Maik Nauka-Interperiodica Publishing",
number = "1",

}

TY - JOUR

T1 - A comprehensive study of interactions between lectins and glycoproteins for the development of effective theranostic nanoagents

AU - Shipunova, V. O.

AU - Nikitin, M. P.

AU - Zelepukin, I. V.

AU - Nikitin, P. I.

AU - Deyev, S. M.

AU - Petrov, R. V.

PY - 2015/9/1

Y1 - 2015/9/1

N2 - A comprehensive study of the interactions between lectins and glycoproteins possessing different glycosylation profiles in the composition of nanoparticles was carried out in order to find specifically interacting protein pairs for the creation of novel classes of multifunctional nanoagets that based on protein-assisted selfassembly. We obtained information about specific interactions of certain lectins with selected glycoproteins as well as about the ability of certain monosaccharides to competitively inhibit binding of glycoproteins with lectins. These protein-mediated interactions may be involved in the formulation of self-assembled nanoparticles for therapy and diagnostics of various diseases.

AB - A comprehensive study of the interactions between lectins and glycoproteins possessing different glycosylation profiles in the composition of nanoparticles was carried out in order to find specifically interacting protein pairs for the creation of novel classes of multifunctional nanoagets that based on protein-assisted selfassembly. We obtained information about specific interactions of certain lectins with selected glycoproteins as well as about the ability of certain monosaccharides to competitively inhibit binding of glycoproteins with lectins. These protein-mediated interactions may be involved in the formulation of self-assembled nanoparticles for therapy and diagnostics of various diseases.

UR - http://www.scopus.com/inward/record.url?scp=84945580997&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84945580997&partnerID=8YFLogxK

U2 - 10.1134/S1607672915050117

DO - 10.1134/S1607672915050117

M3 - Article

AN - SCOPUS:84945580997

VL - 464

SP - 315

EP - 318

JO - Doklady Biochemistry and Biophysics

JF - Doklady Biochemistry and Biophysics

SN - 1607-6729

IS - 1

ER -