Voltammetric study of the antioxidant properties of catalase and superoxide dismutase

E. I. Korotkova, O. I. Lipskikh, M. A. Kiseleva, V. V. Ivanov

Research output: Contribution to journalArticle

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Abstract

The antioxidant properties of catalase and superoxide dismutase (SOD) have been studied by voltammetry. The effect of pH on the antioxidant properties of catalase and SOD has been evaluated. It is established that the antioxidant activity of both enzymes is maximum at pH 6.86. Mechanisms of the interaction of enzymes with reactive oxygen species are considered. Antioxidant activity criterion (IC50) for SOD and some copper complexes have been estimated by voltammetry and spectrophotometry.

Original languageEnglish
Pages (from-to)485-487
Number of pages3
JournalPharmaceutical Chemistry Journal
Volume42
Issue number8
DOIs
Publication statusPublished - Aug 2008

Fingerprint

Catalase
Superoxide Dismutase
Antioxidants
Spectrophotometry
Enzymes
Inhibitory Concentration 50
Copper
Reactive Oxygen Species

ASJC Scopus subject areas

  • Drug Discovery
  • Pharmacology

Cite this

Voltammetric study of the antioxidant properties of catalase and superoxide dismutase. / Korotkova, E. I.; Lipskikh, O. I.; Kiseleva, M. A.; Ivanov, V. V.

In: Pharmaceutical Chemistry Journal, Vol. 42, No. 8, 08.2008, p. 485-487.

Research output: Contribution to journalArticle

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