Abstract
The antioxidant properties of catalase and superoxide dismutase (SOD) have been studied by voltammetry. The effect of pH on the antioxidant properties of catalase and SOD has been evaluated. It is established that the antioxidant activity of both enzymes is maximum at pH 6.86. Mechanisms of the interaction of enzymes with reactive oxygen species are considered. Antioxidant activity criterion (IC50) for SOD and some copper complexes have been estimated by voltammetry and spectrophotometry.
| Original language | English |
|---|---|
| Pages (from-to) | 485-487 |
| Number of pages | 3 |
| Journal | Pharmaceutical Chemistry Journal |
| Volume | 42 |
| Issue number | 8 |
| DOIs | |
| Publication status | Published - Aug 2008 |
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ASJC Scopus subject areas
- Drug Discovery
- Pharmacology
Cite this
Voltammetric study of the antioxidant properties of catalase and superoxide dismutase. / Korotkova, E. I.; Lipskikh, O. I.; Kiseleva, M. A.; Ivanov, V. V.
In: Pharmaceutical Chemistry Journal, Vol. 42, No. 8, 08.2008, p. 485-487.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Voltammetric study of the antioxidant properties of catalase and superoxide dismutase
AU - Korotkova, E. I.
AU - Lipskikh, O. I.
AU - Kiseleva, M. A.
AU - Ivanov, V. V.
PY - 2008/8
Y1 - 2008/8
N2 - The antioxidant properties of catalase and superoxide dismutase (SOD) have been studied by voltammetry. The effect of pH on the antioxidant properties of catalase and SOD has been evaluated. It is established that the antioxidant activity of both enzymes is maximum at pH 6.86. Mechanisms of the interaction of enzymes with reactive oxygen species are considered. Antioxidant activity criterion (IC50) for SOD and some copper complexes have been estimated by voltammetry and spectrophotometry.
AB - The antioxidant properties of catalase and superoxide dismutase (SOD) have been studied by voltammetry. The effect of pH on the antioxidant properties of catalase and SOD has been evaluated. It is established that the antioxidant activity of both enzymes is maximum at pH 6.86. Mechanisms of the interaction of enzymes with reactive oxygen species are considered. Antioxidant activity criterion (IC50) for SOD and some copper complexes have been estimated by voltammetry and spectrophotometry.
UR - http://www.scopus.com/inward/record.url?scp=57849164498&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=57849164498&partnerID=8YFLogxK
U2 - 10.1007/s11094-008-0156-0
DO - 10.1007/s11094-008-0156-0
M3 - Article
VL - 42
SP - 485
EP - 487
JO - Pharmaceutical Chemistry Journal
JF - Pharmaceutical Chemistry Journal
SN - 0091-150X
IS - 8
ER -