The voltammetric behavior of nifedipine (NFD) has been studied with two different types of working electrodes (hanging mercury drop mini-electrode (HMDmE) and mercury meniscus silver solid amalgam electrode (m-AgSAE)) using differential pulse voltammetry (DPV). The optimal conditions for DPV determination are: a mixture of Britton-Robinson (BR) buffer pH 8 with methanol in three different ratios (1:1, 9:1, 99:1), respectively, in the concentration range of 0.2 to 20 μmol/L. The limit of quantification (LQ) was found to be 0.12 μmol/L (HMDmE) and 1.2 μmol/L (m-AgSAE). Attempts to increase the sensitivity using adsorptive stripping DPV at both HMDmE and m-AgSAE were not successful. Using the optimum conditions, the practical application of the newly developed method has been verified on the determination of NFD in spiked samples of drinking and river water.
|Number of pages||14|
|Journal||International Journal of Electrochemical Science|
|Publication status||Published - 1 Jan 2015|
- Differential pulse voltammetry
- Hanging mercury drop mini-electrode
- Mercury meniscus silver solid amalgam electrode
ASJC Scopus subject areas