Voltammetric determination of genotoxic nitro derivatives of fluorene and 9-fluorenone using a mercury meniscus modified silver solid amalgam electrode

Vlastimil Vyskočil, Tomáš Navrátil, Petra Polášková, Jiří Barek

Research output: Contribution to journalArticle

34 Citations (Scopus)

Abstract

Voltammetric behavior of selected genotoxic nitro compounds (2-nitrofluorene, 2,7-dinitrofluorene, 2-nitro-9-fluorenone and 2,7-dinitro-9-fluorenone) has been investigated using direct current voltammetry (DCV), differential pulse voltammetry (DPV) and adsorptive stripping differential pulse voltammetry (AdSDPV) at a mercury meniscus modified silver solid amalgam electrode (m-AgSAE). The optimum conditions have been found for their determination in a 1:1 mixture of methanol and aqueous Britton - Robinson buffer solution, with the limits of quantification, (LOQ), 2, 0.3, 0.5, and 0.5 μmol L-1 (DCV at m-AgSAE) and 0.2, 0.2, 0.4, and 0.2 μmol L-1 (DPV at m-AgSAE) for 2-nitrofluorene, 2,7-dinitrofluorene, 2-nitro-9-fluorenone, and 2,7-dinitro-9-fluorenone, respectively. An attempt at increasing the sensitivity using AdSDPVat m-AgSAE was successful only for 2-nitrofluorene (LOQ1/4 2 μmol L-1). Practical applicability of the newly developed methods was verified on direct determination of the studied compounds in drinking and river waters with LOQs~10-7 mol L-1 for all the studied compounds.

Original languageEnglish
Pages (from-to)2034-2042
Number of pages9
JournalElectroanalysis
Volume22
Issue number17-18
DOIs
Publication statusPublished - 20 Sep 2010
Externally publishedYes

Fingerprint

Mercury amalgams
Mercury (metal)
Voltammetry
Mercury
Silver
Derivatives
Electrodes
Nitro Compounds
Methanol
Buffers
Rivers
9-fluorenone
fluorene
2,7-dinitrofluorenone
2-nitro-9-fluorenone
2,7-dinitrofluorene
Water

Keywords

  • 2,7-Dinitro-9-fluorenone
  • 2,7-Dinitrofluorene
  • 2-Nitro-9-fluorenone
  • 2-Nitrofluorene
  • Drinking water
  • River water
  • Silver solid amalgam electrode
  • Voltammetry

ASJC Scopus subject areas

  • Analytical Chemistry
  • Electrochemistry

Cite this

Voltammetric determination of genotoxic nitro derivatives of fluorene and 9-fluorenone using a mercury meniscus modified silver solid amalgam electrode. / Vyskočil, Vlastimil; Navrátil, Tomáš; Polášková, Petra; Barek, Jiří.

In: Electroanalysis, Vol. 22, No. 17-18, 20.09.2010, p. 2034-2042.

Research output: Contribution to journalArticle

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AU - Polášková, Petra

AU - Barek, Jiří

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N2 - Voltammetric behavior of selected genotoxic nitro compounds (2-nitrofluorene, 2,7-dinitrofluorene, 2-nitro-9-fluorenone and 2,7-dinitro-9-fluorenone) has been investigated using direct current voltammetry (DCV), differential pulse voltammetry (DPV) and adsorptive stripping differential pulse voltammetry (AdSDPV) at a mercury meniscus modified silver solid amalgam electrode (m-AgSAE). The optimum conditions have been found for their determination in a 1:1 mixture of methanol and aqueous Britton - Robinson buffer solution, with the limits of quantification, (LOQ), 2, 0.3, 0.5, and 0.5 μmol L-1 (DCV at m-AgSAE) and 0.2, 0.2, 0.4, and 0.2 μmol L-1 (DPV at m-AgSAE) for 2-nitrofluorene, 2,7-dinitrofluorene, 2-nitro-9-fluorenone, and 2,7-dinitro-9-fluorenone, respectively. An attempt at increasing the sensitivity using AdSDPVat m-AgSAE was successful only for 2-nitrofluorene (LOQ1/4 2 μmol L-1). Practical applicability of the newly developed methods was verified on direct determination of the studied compounds in drinking and river waters with LOQs~10-7 mol L-1 for all the studied compounds.

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