Voltammetric determination of drugs in complicated multy-component systems

Galina Slepchenko, Liubov Anisimova, Victoria Fedorchuk, Valentina Slipchenco, Eugenia Slepchenko, Elena Valentionovna Mikheeva, Yury Akeneyev, Nina Pikula

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The introduction of foodstuffs, biologically active additives, animal feeds certification procedure requires development of express, high sensitive and accurate methods of determination of a number of chemical organic compounds. Vitamins and some flavonoids belong to alimentary organic substances required in small amounts. The antibiotics contained in foods and biologically active additives based on milk stuffs render toxic activity on human organism. One should pay attention on the high level of contaminating by chloramphenicol, streptomycin, tetracycline - the antibiotics with dangerous side - effects. The optimal conditions of quantitative chemical analysis antibiotics mentioned above, water- and liposoluble vitamins in foodstuffs and feeds, pharmaceuticals (powders, eye drops, tablets etc.) have been determined. The stage of preliminary isolation of determined substances at pretreatment before voltammetric measurements has been considerable simplified. The interference of water-soluble proteins has been eliminated by their hydrolysis, saponification and salting-out with organic solvents and salts. The designed methods allow to control the content of antibiotics, vitamins at levels of the demanded by the normative documents. The methods are certificated.

Original languageEnglish
Title of host publication8th Korea-Russia International Symposium on Science and Technology - Proceedings: KORUS 2004
Pages84-88
Number of pages5
Volume2
Publication statusPublished - 2004
Event8th Korea-Russia International Symposium on Science and Technology, KORUS 2004 - Tomsk, Russian Federation
Duration: 26 Jun 20043 Jul 2004

Other

Other8th Korea-Russia International Symposium on Science and Technology, KORUS 2004
CountryRussian Federation
CityTomsk
Period26.6.043.7.04

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Keywords

  • Antibiotics
  • Cephazolin
  • Chloramphenicol
  • Determination
  • Streptomycin
  • Tetracyclin
  • Voltammetry

ASJC Scopus subject areas

  • Engineering(all)

Cite this

Slepchenko, G., Anisimova, L., Fedorchuk, V., Slipchenco, V., Slepchenko, E., Mikheeva, EV., ... Pikula, N. (2004). Voltammetric determination of drugs in complicated multy-component systems. In 8th Korea-Russia International Symposium on Science and Technology - Proceedings: KORUS 2004 (Vol. 2, pp. 84-88)